A salt represented by formula (I):

##STR00001##

wherein R.sup.1 and R.sup.2 each independently represent a hydroxy group, —O—R.sup.10, —O—CO—O—R.sup.10 or —O-L.sup.1-CO—O—R.sup.10; L.sup.1 represents an alkanediyl group having 1 to 6 carbon atoms; R.sup.4, R.sup.5, R.sup.7 and R.sup.8 each independently represent a halogen atom, an alkyl fluoride group having 1 to 12 carbon atoms or a hydrocarbon group having 1 to 18 carbon atoms, the hydrocarbon group may have a substituent, and —CH.sub.2— included in the hydrocarbon group may be replaced by —O—, —CO—, —S— or —SO.sub.2—; R.sup.10 represents an acid-labile group; X.sup.1 and X.sup.2 each independently represent an oxygen atom or a sulfur atom; m1 represents an integer of 1 to 5, m2 and m8 represent an integer of 0 to 5, m4, m5 and m7 represent an integer of 0 to 4; and AI.sup.− represents an organic anion.

The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.

The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.

The present invention relates to triarylmethane compounds of the formula (I), which suitable as monomers for preparing thermoplastic resins having beneficial optical properties and which can be used for producing optical devices. R.sup.1, R.sup.2 are e.g. hydrogen; Y is an alkylene group having 2, 3 or 4 carbon atoms, Ar is selected from mono- or polycyclic aryl and mono- or polycyclic hetaryl; X.sup.1, X.sup.2, X.sup.3, X.sup.4 are CH, C—R.sup.x or N, provided that in each ring at most two of X.sup.1, X.sup.2, X.sup.3, X.sup.4 are N; R.sup.x is e.g. halogen, CN or CH═CH.sub.2. The invention also relates to thermoplastic resins comprising a polymerized unit of the compound of formula (I). ##STR00001##

Embodiments in accordance with the present invention encompass compositions encompassing a latent organo-ruthenium compound and a pyridine compound along with one or more monomers which undergo ring open metathesis polymerization (ROMP) when said composition is exposed to suitable actinic radiation to form a substantially transparent film. Surprisingly, the compositions are very stable at ambient conditions to temperatures up to 80° C. for several days and undergo mass polymerization when subject only to actinic radiation. Accordingly, compositions of this invention are useful in various opto-electronic applications, including as 3D printing materials, coatings, encapsulants, fillers, leveling agents, among others.

Embodiments in accordance with the present invention encompass compositions encompassing a latent organo-ruthenium compound and a pyridine compound along with one or more monomers which undergo ring open metathesis polymerization (ROMP) when said composition is exposed to suitable actinic radiation to form a substantially transparent film. Surprisingly, the compositions are very stable at ambient conditions to temperatures up to 80° C. for several days and undergo mass polymerization when subject only to actinic radiation. Accordingly, compositions of this invention are useful in various opto-electronic applications, including as 3D printing materials, coatings, encapsulants, fillers, leveling agents, among others.

The present invention relates to compounds of the formula (I), which are suitable as monomers for preparing thermoplastic resins having beneficial optical properties and which can be used for producing optical devices: where A.sup.1, A.sup.2 are selected from mono- or bicyclic aromatic radicals and mono- or bicyclic heteroaromatic radicals, X represents e.g. a single bond, O, NH, CR.sup.6R.sup.7, Y is e.g. absent or represents a single bond, O, NH, CR.sup.8R.sup.9; R.sup.1, R.sup.2 are hydrogen, a radical Ar′ or a radical R.sup.a; R.sup.3 is Alk, O-Alk′-, O-Alk′-[O-Alk′].sub.0, O—CH.sub.2—Ar—C(O)—, O—C(O)—Ar—C(O)— or O-Alk-C(O)—, where in the last five moieties the left O is bound to A.sup.1 and A.sup.2, respectively, m, n are 0, 1 or 2; o is an integer from 1 to 10; R.sup.4, R.sup.5 are e.g. selected from CN and a radical R.sup.a; R.sup.6, R.sup.8 are e.g. selected from hydrogen, a radical Ar′ and a radical R.sup.a; R.sup.7, R.sup.9 are e.g. selected from hydrogen, C.sub.1-C.sub.4-alkyl and a radical Ar′; R.sup.a is selected from the group consisting of C≡C—R.sup.11 and Ar—C≡C—R.sup.11; R.sup.11 is e.g. selected from hydrogen, methyl, mono- or polycyclic aryl having from 6 to 26 carbon atoms and mono- or polycyclic hetaryl having a total of 5 to 26 atoms, which are ring members, where 1, 2, 3 or 4 of the ring atoms of hetaryl are selected from nitrogen, sulphur and oxygen, while the remainder of these atoms are carbon atoms, where mono- or polycyclic aryl are unsubstituted or substituted; and Ar is e.g. phenylene or naphthylene. The invention also relates to thermoplastic resins comprising a polymerized unit of the compound of formula (I) and to optical devices made of such resins.

##STR00001##

The present invention relates to compounds of the formula (I), which are suitable as monomers for preparing thermoplastic resins having beneficial optical properties and which can be used for producing optical devices: where A.sup.1, A.sup.2 are selected from mono- or bicyclic aromatic radicals and mono- or bicyclic heteroaromatic radicals, X represents e.g. a single bond, O, NH, CR.sup.6R.sup.7, Y is e.g. absent or represents a single bond, O, NH, CR.sup.8R.sup.9; R.sup.1, R.sup.2 are hydrogen, a radical Ar′ or a radical R.sup.a; R.sup.3 is Alk, O-Alk′-, O-Alk′-[O-Alk′].sub.0, O—CH.sub.2—Ar—C(O)—, O—C(O)—Ar—C(O)— or O-Alk-C(O)—, where in the last five moieties the left O is bound to A.sup.1 and A.sup.2, respectively, m, n are 0, 1 or 2; o is an integer from 1 to 10; R.sup.4, R.sup.5 are e.g. selected from CN and a radical R.sup.a; R.sup.6, R.sup.8 are e.g. selected from hydrogen, a radical Ar′ and a radical R.sup.a; R.sup.7, R.sup.9 are e.g. selected from hydrogen, C.sub.1-C.sub.4-alkyl and a radical Ar′; R.sup.a is selected from the group consisting of C≡C—R.sup.11 and Ar—C≡C—R.sup.11; R.sup.11 is e.g. selected from hydrogen, methyl, mono- or polycyclic aryl having from 6 to 26 carbon atoms and mono- or polycyclic hetaryl having a total of 5 to 26 atoms, which are ring members, where 1, 2, 3 or 4 of the ring atoms of hetaryl are selected from nitrogen, sulphur and oxygen, while the remainder of these atoms are carbon atoms, where mono- or polycyclic aryl are unsubstituted or substituted; and Ar is e.g. phenylene or naphthylene. The invention also relates to thermoplastic resins comprising a polymerized unit of the compound of formula (I) and to optical devices made of such resins.

##STR00001##

Provided is a compound represented by General Formula (1) ##STR00001## in General Formula (1), Ar.sub.1 and Ar.sub.2 independently represent a group selected from the following Formulae, ##STR00002##

The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haematopoietic system including the haematologic system in human and veterinary medicine.