A method for efficiently catalyzing furfural to prepare cyclopentanone, and a catalyst and preparation method therefor, are disclosed, in the field of biomass catalytic conversion. The catalyst comprises uniformly dispersed metal active center nanoparticles and oxides obtained by LDHs calcination. The metal active center is single atom Pt/Cu alloy; the LDHs is used as a precursor to prepare a Cu-containing catalyst precursor; after a reduction in H.sub.2 atmosphere, small amount of Pt.sup.2+ is used for reacting with the Cu-containing catalyst precursor to obtain a monoatomic Pt/Cu catalyst; said catalyst is used to catalyze hydrogenation of an aqueous phase of furfural to prepare cyclopentanone, wherein the reaction temperature is 120-250 C., the reaction pressure is 0.1-5 MPa, the reaction time is 0.5-24 hours, and the reaction solvent is ultrapure water. Low-cost and efficient, the catalyst catalyzes the hydrogenation of an aqueous phase of furfural to prepare cyclopentanone. When the reaction is carried out at 160 C. at an initial pressure of 0.1 MPa for 1 hour, the furfural is completely converted, and the yield of the cyclopentanone reaches 99%.

A method for efficiently catalyzing furfural to prepare cyclopentanone, and a catalyst and preparation method therefor, are disclosed, in the field of biomass catalytic conversion. The catalyst comprises uniformly dispersed metal active center nanoparticles and oxides obtained by LDHs calcination. The metal active center is single atom Pt/Cu alloy; the LDHs is used as a precursor to prepare a Cu-containing catalyst precursor; after a reduction in H.sub.2 atmosphere, small amount of Pt.sup.2+ is used for reacting with the Cu-containing catalyst precursor to obtain a monoatomic Pt/Cu catalyst; said catalyst is used to catalyze hydrogenation of an aqueous phase of furfural to prepare cyclopentanone, wherein the reaction temperature is 120-250 C., the reaction pressure is 0.1-5 MPa, the reaction time is 0.5-24 hours, and the reaction solvent is ultrapure water. Low-cost and efficient, the catalyst catalyzes the hydrogenation of an aqueous phase of furfural to prepare cyclopentanone. When the reaction is carried out at 160 C. at an initial pressure of 0.1 MPa for 1 hour, the furfural is completely converted, and the yield of the cyclopentanone reaches 99%.

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, for use as a drug, especially as an antibiotic. The present invention also relates to a pharmaceutical composition comprising said compound of formula (I) and at least one pharmaceutically acceptable excipient. The present invention further concerns a method of preparation of a compound of formula (I).

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The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, for use as a drug, especially as an antibiotic. The present invention also relates to a pharmaceutical composition comprising said compound of formula (I) and at least one pharmaceutically acceptable excipient. The present invention further concerns a method of preparation of a compound of formula (I).

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A method of depolymerizing a lignin includes oxidizing the lignin to provide an oxidized lignin wherein benzylic OH of -O-4 linkages have been converted to carbonyl. The oxidized lignin is depolymerized with a metal selected from the group consisting of zinc, magnesium, aluminum and titanium or mixtures thereof, in the presence of an ammonium salt or carbon dioxide. Also described are methods for manufacturing phenolic products from lignin and a method for the cleavage of a -O-4 linkage in a substrate.

A method of depolymerizing a lignin includes oxidizing the lignin to provide an oxidized lignin wherein benzylic OH of -O-4 linkages have been converted to carbonyl. The oxidized lignin is depolymerized with a metal selected from the group consisting of zinc, magnesium, aluminum and titanium or mixtures thereof, in the presence of an ammonium salt or carbon dioxide. Also described are methods for manufacturing phenolic products from lignin and a method for the cleavage of a -O-4 linkage in a substrate.

The invention relates to anthracycline derivative compounds for treating tumor diseases, and related methods, compositions, and kits.

The invention relates to anthracycline derivative compounds for treating tumor diseases, and related methods, compositions, and kits.

In a cross coupling reaction, in a case where a halogen atom is selected as the leaving group of the raw material compound, a harmful halogen waste forms as a by-product after the reaction, and disposal of the waste liquid is complicated and environmental burden is high. In a carbon-hydrogen activation cross coupling reaction which requires no halogen atom as the leaving group, although no halogen waste forms as a by-product, the reaction substrate is considerably restricted, and the reaction remains a limited molecular construction method. A method for producing an aromatic compound, which comprises subjecting an aromatic nitro compound and a boronic acid compound to a cross coupling reaction in the presence of a metal catalyst.

In a cross coupling reaction, in a case where a halogen atom is selected as the leaving group of the raw material compound, a harmful halogen waste forms as a by-product after the reaction, and disposal of the waste liquid is complicated and environmental burden is high. In a carbon-hydrogen activation cross coupling reaction which requires no halogen atom as the leaving group, although no halogen waste forms as a by-product, the reaction substrate is considerably restricted, and the reaction remains a limited molecular construction method. A method for producing an aromatic compound, which comprises subjecting an aromatic nitro compound and a boronic acid compound to a cross coupling reaction in the presence of a metal catalyst.