C07C49/747

CYCLOPENTENONES DERIVATIVES AND THEIR USE AS ANTIBIOTICS

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, for use as a drug, especially as an antibiotic. The present invention also relates to a pharmaceutical composition comprising said compound of formula (I) and at least one pharmaceutically acceptable excipient. The present invention further concerns a method of preparation of a compound of formula (I).

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CYCLOPENTENONES DERIVATIVES AND THEIR USE AS ANTIBIOTICS

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, for use as a drug, especially as an antibiotic. The present invention also relates to a pharmaceutical composition comprising said compound of formula (I) and at least one pharmaceutically acceptable excipient. The present invention further concerns a method of preparation of a compound of formula (I).

##STR00001##

Compounds from invasive Salvinias and methods of using the same

In some embodiments, the compositions and methods relate to compounds isolated from plants in the Salviniaceae family, pharmaceutical compositions comprising the same, and methods of using the same.

Compounds from invasive Salvinias and methods of using the same

In some embodiments, the compositions and methods relate to compounds isolated from plants in the Salviniaceae family, pharmaceutical compositions comprising the same, and methods of using the same.

PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SAME
20240158340 · 2024-05-16 ·

The present invention relates to a method for producing an ?-aryl substituted carbonyl compound (e.g., an ?-aryl substituted cyclic ketone) from a carbonyl compound (e.g., a cyclic ketone) using an aryl halide or a heteroaryl halide and a photocatalyst (e.g., acridinium, helicenium, angulenium, or a combination thereof) in the presence of an amine compound. The method of the present invention is particularly useful in producing an ?-aryl substituted carbonyl compound (e.g., an ?-aryl substituted cyclic ketone) from an unactivated carbonyl compound (e.g., an unactivated cyclic ketone).

PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SAME
20240158340 · 2024-05-16 ·

The present invention relates to a method for producing an ?-aryl substituted carbonyl compound (e.g., an ?-aryl substituted cyclic ketone) from a carbonyl compound (e.g., a cyclic ketone) using an aryl halide or a heteroaryl halide and a photocatalyst (e.g., acridinium, helicenium, angulenium, or a combination thereof) in the presence of an amine compound. The method of the present invention is particularly useful in producing an ?-aryl substituted carbonyl compound (e.g., an ?-aryl substituted cyclic ketone) from an unactivated carbonyl compound (e.g., an unactivated cyclic ketone).

Abietane type diterpene compound, preparation method and application thereof

Disclosed are an abietane type diterpene compound, a preparation method and an application thereof, relating to the technical field of anti-tumor compounds, where the compound has a chemical structure as shown in the following formula I: ##STR00001##
Leucosceptrum canum is extracted to prepare the abietane type diterpene compound according to the present application, and the prepared compound is effectively applied in inhibiting human lung cancer cell A549 and human myeloid leukemia cell HL-60.

Abietane type diterpene compound, preparation method and application thereof

Disclosed are an abietane type diterpene compound, a preparation method and an application thereof, relating to the technical field of anti-tumor compounds, where the compound has a chemical structure as shown in the following formula I: ##STR00001##
Leucosceptrum canum is extracted to prepare the abietane type diterpene compound according to the present application, and the prepared compound is effectively applied in inhibiting human lung cancer cell A549 and human myeloid leukemia cell HL-60.

ABIETANE TYPE DITERPENE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF
20240150273 · 2024-05-09 ·

Disclosed are an abietane type diterpene compound, a preparation method and an application thereof, relating to the technical field of anti-tumor compounds, where the compound has a chemical structure as shown in the following formula I:

##STR00001##

Leucosceptrum canum is extracted to prepare the abietane type diterpene compound according to the present application, and the prepared compound is effectively applied in inhibiting human lung cancer cell A549 and human myeloid leukemia cell HL-60.

ABIETANE TYPE DITERPENE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF
20240150273 · 2024-05-09 ·

Disclosed are an abietane type diterpene compound, a preparation method and an application thereof, relating to the technical field of anti-tumor compounds, where the compound has a chemical structure as shown in the following formula I:

##STR00001##

Leucosceptrum canum is extracted to prepare the abietane type diterpene compound according to the present application, and the prepared compound is effectively applied in inhibiting human lung cancer cell A549 and human myeloid leukemia cell HL-60.