The present invention concerns a process for the obtention of a halogenated carboxylic halide having a reduced content of impurities, a fraction of the halogenated carboxylic halide having a reduced content of impurities, and its use in the manufacture of agriculturally and pharmaceutically active compounds.

A photochemical reactor and a photo-oxidation process for manufacturing organic compounds are disclosed. The photo-oxidation generates polyfluorochloro- and/or perfluorocarboxylic acid chloride compounds, in particular halogenated acetyl chlorides, such as polyfluorochloro- and/or perfluoro acetyl chloride. The photo-oxidation process is exothermic. The reactor has a channel or a channels system, including tubes, pipes, or coils, such as coiled tubes or pipes, and, optionally, gasket installations in combination with tubes/pipes, and interior installations, such as microtubes or micropipes. The interior installations avoid formation of hot spots and provide for very good mixing of the reaction medium, such that the photochemical reactions do not only take place in part of reaction medium within a few mm around the UV lighting source. Formation of oxidizing by-products is eliminated, which may otherwise be formed during the photochemical oxidation and possibly accumulate in the photochemical reactor and/or process equipment, such as cooling traps and piping systems.

A photochemical reactor and a photo-oxidation process for manufacturing organic compounds are disclosed. The photo-oxidation generates polyfluorochloro- and/or perfluorocarboxylic acid chloride compounds, in particular halogenated acetyl chlorides, such as polyfluorochloro- and/or perfluoro acetyl chloride. The photo-oxidation process is exothermic. The reactor has a channel or a channels system, including tubes, pipes, or coils, such as coiled tubes or pipes, and, optionally, gasket installations in combination with tubes/pipes, and interior installations, such as microtubes or micropipes. The interior installations avoid formation of hot spots and provide for very good mixing of the reaction medium, such that the photochemical reactions do not only take place in part of reaction medium within a few mm around the UV lighting source. Formation of oxidizing by-products is eliminated, which may otherwise be formed during the photochemical oxidation and possibly accumulate in the photochemical reactor and/or process equipment, such as cooling traps and piping systems.

Described herein are three methods for making halogenated fluorinated ether-containing compounds using a fluorinated olefin or hexafluoropropylene oxide.

Described herein are three methods for making halogenated fluorinated ether-containing compounds using a fluorinated olefin or hexafluoropropylene oxide.

The present invention relates to a process for manufacturing haloacetamides of formula (I), ##STR00001##
comprising sub-step (a): reacting halones of formula (II) with oleum; followed by sub-step (b): reacting the reaction mixture obtained in sub-step (a) with an amine of formula (IV) optionally in the presence of a base;
wherein the variables are defined according to the description.

The present invention relates to a process for manufacturing haloacetamides of formula (I), ##STR00001##
comprising sub-step (a): reacting halones of formula (II) with oleum; followed by sub-step (b): reacting the reaction mixture obtained in sub-step (a) with an amine of formula (IV) optionally in the presence of a base;
wherein the variables are defined according to the description.

An object is to provide a method of producing a carboxylic acid fluoride at an increased product yield in a reaction system without forming HCl as a by-product, in other words, without forming a complex between HCl and a carboxylic acid fluoride as a product. The method comprising reacting a carboxylic acid chloride with a metal fluoride. In this production method, the carboxylic acid is a carboxylic acid having a carbon number of 1 to 7, the carboxylic acid is a carboxylic acid substituted with fluorine, or the carboxylic acid is trifluoroacetic acid.

An object is to provide a method of producing a carboxylic acid fluoride at an increased product yield in a reaction system without forming HCl as a by-product, in other words, without forming a complex between HCl and a carboxylic acid fluoride as a product. The method comprising reacting a carboxylic acid chloride with a metal fluoride. In this production method, the carboxylic acid is a carboxylic acid having a carbon number of 1 to 7, the carboxylic acid is a carboxylic acid substituted with fluorine, or the carboxylic acid is trifluoroacetic acid.