Biological navigation devices and methods are disclosed. The devices can be used as or to support colonoscopies or endoscopes. The devices can have longitudinally extensible cells that can be selectively inflated. The devices can have articulable links. The devices can be removably attached to elongated elements, such as colonoscopes or other endoscopes.

This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an immunosuppressant.

An endoscope apparatus includes an elongated insertion portion, a self-propelling mechanism configured to be rotatably driven to advance and retract the insertion portion, and a motor configured to supply a drive force to the self-propelling mechanism. A control apparatus for the endoscope apparatus includes a current controller configured to supply a motor current to the motor to control driving of the motor, a motor current detector configured to detect a value of the motor current, a motor current change amount detector configured to detect an amount of change in the value of the motor current, and a limit controller configured to stop a supply of the motor current by the current controller according to the amount of change.

Introduced here is an ingestible device comprising a capsule having a central axis therethrough, at least one propulsion component, and at least one motor configured to supply motive power to the propulsion component(s). The propulsion component(s) may be disposed at locations radially offset from the central axis. Upon receiving input indicative of a request to alter a position and/or an orientation of the ingestible device, the motor(s) can supply motive power to some or all of the propulsion component(s) to cause movement of the ingestible device.

Embodiments of the disclosure are drawn to a medical device delivery system. The system may include a shaft having a proximal end and a distal end. The device may also include a visualization system at a distal region of the shaft. The system may further include at least one latching structure configured to extend beyond the distal end of the shaft and retract within the distal region of the shaft and at least one advancement mechanism configured to extend beyond the distal end of the shaft to pull the shaft in a distal direction.

An insertion device includes an insertion portion in which a movable member is held in contact with an outer circumferential surface of a hollow cylindrical member. When drive power is transmitted from the hollow cylindrical member to the movable member as the hollow cylindrical member is rotated about a longitudinal axis of the insertion portion, the movable member is rotated around its own axis parallel to the longitudinal axis and moved around the longitudinal axis. The insertion portion includes a membrane covering the movable member from an outer circumferential side thereof. The membrane urges the movable member toward the longitudinal axis, thereby pressing the movable member against the outer circumferential surface of the hollow cylindrical member.

A medical system includes one or more medical devices for intra-body conveyance which include a host structure that defines an interior area, one or more data gathering system, one or more means for communication, for transmitting data from the data gathering systems. The medical device is configurable into a peripheral boundary of a size adapted to fit in a lumen of a living organism. The medical system includes an external processing device configured to receive the transmitted data from the means for communication. The external processing system is configured to perform data analysis on the data received from the medical device.

The present invention discloses a capsule endoscope with specific gravity control. The capsule endoscope comprises a housing to enclose various components, an inflatable device attached to a first longitudinal end of the capsule unit and an enteric coated shell attached to the first longitudinal end of the capsule unit to enclose the inflatable device between the enteric coated shell and the capsule unit. The various components include a camera sub-system for capturing image frames. The inflatable device comprises an inflatable membrane and an effervescent formulation inside the inflatable membrane. The enteric coated shell fits tightly onto the first longitudinal end of the capsule unit to prevent body liquid from leaking into a space between the enteric coated shell and the capsule unit when the capsule unit travels in human gastrointestinal tract after being swallowed.

An endoscopic deployment device includes a body mountable on an endoscopic device, the body having a movable carrier couplable to an end effector device, the end effector device having an end effector shaft covered by an outer sheath and an end effector extending from a distal end of the end effector shaft, the outer sheath being sized and shaped for insertion through a working channel of the endoscopic device, the body having a carrier channel for the carrier to slide therein, wherein the end effecter is actuatable between an open position and a closed position; and a motor having a drive shaft coupled to the carrier, rotation of the drive shaft sliding the carrier in the carrier channel and actuating the end effector in response to a signal from one or more actuation buttons; wherein at least one vibration motor generates vibrations as an angular position of the motor changes.

Introduced here is an ingestible device comprising a capsule having a central axis therethrough, at least one propulsion component, and at least one motor configured to supply motive power to the propulsion component(s). The propulsion component(s) may be disposed at locations radially offset from the central axis. Upon receiving input indicative of a request to alter a position and/or an orientation of the ingestible device, the motor(s) can supply motive power to some or all of the propulsion component(s) to cause movement of the ingestible device.