A method for producing 1,3-butadiene from a 1,4-butanediol feedstock: One step for esterification of 1,4-butanediol, One step for pyrolysis of 1,4-butanediol diester, producing butadiene.

The invention pertains to a method for converting butanediol into butadiene that is fed with a butanediol feedstock, where said method comprises at least an esterification step, a pyrolysis step, and a step for separation of the pyrolysis effluent comprising at least one section for cooling said pyrolysis effluent and producing a liquid pyrolysis effluent and a steam pyrolysis effluent and a gas-liquid washing section that is fed at the top with a fraction of the butanediol diester effluent obtained from the esterification step and at the bottom with the steam pyrolysis effluent, where said section produces a butadiene effluent at the top and a washing effluent at the bottom.

The invention pertains to a method for converting butanediol into butadiene that is fed with a butanediol feedstock, where said method comprises at least an esterification step, a pyrolysis step, and a step for separation of the pyrolysis effluent comprising at least one section for cooling said pyrolysis effluent and producing a liquid pyrolysis effluent and a steam pyrolysis effluent and a gas-liquid washing section that is fed at the top with a fraction of the butanediol diester effluent obtained from the esterification step and at the bottom with the steam pyrolysis effluent, where said section produces a butadiene effluent at the top and a washing effluent at the bottom.

A series of novel bis(hydroxymethyl) alkanoate derivatives of curcuminoids were designed, and synthesized, which show anticancer activity, and in particular to breast cancer, colon cancer, and prostate cancer.

This disclosure relates to cannabinoid derivatives having the structure of formula (I), pharmaceutical compositions comprising them, and methods of using the cannabinoid derivatives in treating or preventing a diseases associated with a cannabinoid receptor in subject in need thereof, wherein the cannabinoid receptor is one or more of CB1, CB2, 5HT1A, 5HT2A, GPR18, GPR55, GPR119, TRPV1, TRPV2, PPAR? or a ?-opioid receptor.

This disclosure relates to cannabinoid derivatives having the structure of formula (I), pharmaceutical compositions comprising them, and methods of using the cannabinoid derivatives in treating or preventing a diseases associated with a cannabinoid receptor in subject in need thereof, wherein the cannabinoid receptor is one or more of CB1, CB2, 5HT1A, 5HT2A, GPR18, GPR55, GPR119, TRPV1, TRPV2, PPAR? or a ?-opioid receptor.

Described is a method of detecting and/or determining levels of incorporation of monolignol ferulate conjugate esters into lignin by derivatizing the lignin, reductively cleaving the lignin, labeling the cleavage products, and then detecting cleavage products derived from monolignol ester conjugates via differential attachment of the label.

Described is a method of detecting and/or determining levels of incorporation of monolignol ferulate conjugate esters into lignin by derivatizing the lignin, reductively cleaving the lignin, labeling the cleavage products, and then detecting cleavage products derived from monolignol ester conjugates via differential attachment of the label.

Disclosed are hydroquinone compounds, preparation methods therefor, and uses thereof in anti-tumor or immunomodulation. The structural formula of the hydroquinone compounds are shown by formula I,

##STR00001##

wherein X is CO or CH.sub.2; Y is NH, O or absent; R is a substituted or unsubstituted alkyl group having at least one carbon atom, a substituted or unsubstituted cycloalkyl group having at least three carbon atoms, a substituted or unsubstituted alkenyl group or alkynyl group having at least two carbon atoms; and a substituted or unsubstituted aryl group or heteroaryl group containing at least four carbon atoms. The compounds provided slowly release 2-tert-butyl-4-methoxyphenol in vivo and maintain stable plasma concentration of 2-tert-butyl-4-methoxyphenol (T=1224 h). The compounds provided by the present invention protect the phenolic hydroxyl group of 2-tert-butyl-4-methoxyphenol, avoid environmental oxidation and increase the environmental stability of drugs containing the compounds.

Methods of synthesis of hypervalent iodine reagents and methods for oxidation of organic compounds are disclosed.