Patent classifications
C07C69/28
TREPROSTINIL DERIVATIVES AND COMPOSITIONS AND USES THEREOF
The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
METHODS FOR ANALYZING P-HYDROQUINONE LEVELS AND RATIOS
Provided herein are compounds and methods of using the compounds for determining levels of, for example, para-hydroquinones in a sample.
Myricanol derivatives and uses thereof for treatment of neurodegenerative diseases
The subject invention pertains to myricanol derivatives, therapeutic compositions, and methods for treatment of neurodegenerative diseases, in particular, neurodegenerative diseases associated with abnormal accumulation of protein tau.
Myricanol derivatives and uses thereof for treatment of neurodegenerative diseases
The subject invention pertains to myricanol derivatives, therapeutic compositions, and methods for treatment of neurodegenerative diseases, in particular, neurodegenerative diseases associated with abnormal accumulation of protein tau.
PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF
The present disclosure discloses prodrugs of gamma-hydroxybutyric acid as well as compositions and uses thereof.
Myricanol Derivatives and Uses Thereof for Treatment of Neurodegenerative Diseases
The subject invention pertains to myricanol derivatives, therapeutic compositions, and methods for treatment of neurodegenerative diseases, in particular, neurodegenerative dieses associated with abnormal accumulation of protein tau.
Myricanol Derivatives and Uses Thereof for Treatment of Neurodegenerative Diseases
The subject invention pertains to myricanol derivatives, therapeutic compositions, and methods for treatment of neurodegenerative diseases, in particular, neurodegenerative dieses associated with abnormal accumulation of protein tau.
Tetrahydro-isohumulone derivatives, methods of making and using
The present application provides novel tetrahydro-isohumulone (THIAA) derivatives and substantially enantiomerically pure compositions and pharmaceutical formulations thereof. The application further provides methods of using the disclosed compounds and compositions to activate PPAR, inhibit inflammation, and treat conditions associated with inflammation and conditions responsive to PPAR modulation such as diabetes.
Tetrahydro-isohumulone derivatives, methods of making and using
The present application provides novel tetrahydro-isohumulone (THIAA) derivatives and substantially enantiomerically pure compositions and pharmaceutical formulations thereof. The application further provides methods of using the disclosed compounds and compositions to activate PPAR, inhibit inflammation, and treat conditions associated with inflammation and conditions responsive to PPAR modulation such as diabetes.
PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF
The present disclosure discloses prodrugs of gamma-hydroxybutyric acid as well as compositions and uses thereof.