An in vivo of insitu bio-matter sample magnified digital image creating device for realtime biopsy determinations having a sharp edged window pocket coupled to housing having an optical and digital magnification path coupled to image detecting sensor logic. The device has an optical two blade window pocket rotatably coupled to a stem mechanically controlled and extendable from mechanism within the housing, the stem having source for at least one fiber optical channel for selected frequency and wavelength light various light sources, an optical two blade window pocket slide component optically coupled to the two blade window pocket fiber optic channel stem distal end, providing light through the two blade window pocket slide normal axis surface for illumination penetrating a bio matter assay or sample for imaging through an optical microscopy magnification path axis to a micrograph image sensor. The resulting image micrographs for digital pathology realtime result determination.

Systems and methods are provided for preparation of orthodontics and prosthodontics. A method may include scanning a patient's teeth to form first 3D data of the patient's teeth including a removable element that obscures part of the dental surfaces of the patient's teeth and non-obscured tooth surfaces, removing the removable element form the patient's teeth so that the removable element no longer obscures the part of the dental surfaces of the patient's teeth, and scanning the previously obscured part of the dental surfaces of the patent's teeth and the non-obscured tooth surfaces.

An imaging system for a patient comprises an imaging probe. The imaging probe comprises: an elongate shaft for insertion into the patient and comprising a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion; a rotatable optical core comprising a proximal end and a distal end, and at least a portion of the rotatable optical core is positioned within the lumen of the elongate shaft; an optical assembly positioned proximate the distal end of the rotatable optical core, the optical assembly configured to direct light to tissue and collect reflected light from the tissue; a damping fluid positioned between the elongate shaft and the rotatable optical core and configured to reduce non-uniform rotation of the optical assembly; and a fluid pressurization element configured to increase the pressure of the damping fluid to reduce the presence of bubbles proximate the optical assembly.

A spectral imaging device includes an imager, a scanning stage to establish relative motion between the imager and a sample in a scanning direction and an optical system controlling a light characteristic of a light beam constituting an image of the sample to the imager. The optical system includes a light varying element to receive the light beam and provide an output light beam with spatially varying light characteristic over a cross-section thereof. A set of redirecting optical elements direct light rays from the sample to form the light beam, and to focus the output light beam onto the imager. A controller controls the scanning stage and the imager to capture a plurality of image frames with an overlap including a defined shift that is greater than 1 pixel along the scanning direction between consecutive image frames. A computing device consolidates image data to provide an image of the sample.

A device and method for imaging vasculature are provided. The device includes an imaging probe to be inserted into a vasculature. The imaging probe emits infrared light through blood toward the vasculature, and gathers reflected from the vasculature for imaging. The device includes an infrared light source optically coupled to the imaging probe to provide infrared light, and an infrared light detector optically to the imaging probe to generate an imaging signal from the reflected light that is gathered. The device further includes a controller coupled to the infrared light source and coupled to the infrared light detector to generate an image of the vasculature from the imaging signal. The controller may employ ballistic photon imaging techniques, gated imaging techniques, polarizing light imaging techniques, structured light imaging techniques, and the like.

Methods and systems for acquiring and/or projecting images from and/or to a target area are provided. Such a method or system can include an optical fiber assembly which may be driven to scan the target area in a scan pattern. The optical fiber assembly may provide multiple effective light sources (e.g., via a plurality of optical fibers) that are axially staggered with respect to an optical system located between the optical fiber and the target area. The optical system may be operable to focus and/or redirect the light from the multiple light sources onto separate focal planes. A composite image may be generated based on light reflected from and/or projected onto the separate focal planes. The composite image may have an extended depth of focus or field spanning over a distance between the separate focal planes while maintaining or improving image resolution.

An endoscope device, an endoscope operation method, and a program are provided. An endoscope device includes a motion pattern identification unit that identifies a single or plurality of motion patterns indicating a specific movement of a scope head of a scope unit, an operation storage unit that stores a single or plurality of pieces of operation information for instructing an operation of the endoscope device, and the single or plurality of motion patterns of the scope head in association with each other, an operation information acquisition unit that acquires the operation information corresponding to the motion pattern from the operation storage unit on the basis of the motion pattern identified by the motion pattern identification unit, and an operation execution unit that executes an operation corresponding to the operation information acquired by the operation information acquisition unit.

A method and system for dynamically providing visual feedback about a quality of data collected during intra-oral scanning Images or light patterns are projected onto an object such as teeth for 3D measurement and for relaying feedback about a quality of the 3D measurement to a user. In this way unsuccessful registrations surface areas of the teeth that have not been acquired yet may be corrected by informing the user to repeat scans at corresponding locations in the intra-oral cavity.

The present disclosure provides a scanning system for scanning an object, including a scanner device including an image sensor for acquiring images; a mounting-interface for detachably mounting at least one of a plurality of types of scanning-tips, wherein each of the plurality of types scanning-tips is configured for providing light to the object in an illumination-mode that differs for each of the plurality of types of scanning-tips.

The disclosed subject matter includes devices and systems for extending the imaging capability of swept, confocally aligned planar excitation (SCAPE) microscopes to in vivo applications. In embodiments, the SCAPE microscope can be implemented as an endoscopic or laparoscopic inspection instrument.