Scopes such as medical imaging camera head devices and methods are provided using light captured by an endoscope system or other medical scope or borescope. At least one polarizing optical element manipulates the polarization properties of image light. The manipulated image light is focused on an image sensor including polarizers for each pixel. Multiple images are produced based sets of pixels having the same orientation of polarizer. The resulting images are combined with high dynamic range techniques.

An endoscope scope includes: an imaging device that acquires image information; a color filter disposed on pixels of the imaging device and in which primary-color pixels and complementary-color pixels coexist; a detector that detects whether or not an image processor that generates an observation image based on the acquired image information via the color filter is compatible with the image information consisting of an array in which the primary-color pixels and the complementary-color pixels coexist; and a converter that performs Bayer-conversion processing for converting the image information to a Bayer array in a case in which the detector detects that the image processor is not compatible with the image information consisting of the array, and that does not perform the Bayer-conversion processing on the image information in a case in which the detector detects that the image processor is compatible with the image information consisting of the array.

An endoscopic imaging system for use in a light deficient environment includes an imaging device having a tube, one or more image sensors, and a lens assembly including at least one optical elements that corresponds to the one or more image sensors. The endoscopic system includes a display for a user to visualize a scene and an image signal processing controller. The endoscopic system includes a light engine having an illumination source generating one or more pulses of electromagnetic radiation and a lumen transmitting one or more pulses of electromagnetic radiation to a distal tip of an endoscope.

An image sensor assembly includes at least one upconverter configured to detect light in a NIR waveband that is received from an object to be imaged and generate, based on the detected light, upconverted light that is outside of the NIR waveband; and at least one image sensor configured to detect the upconverted light.

Improved fluorescent imaging and other sensor data imaging processes, including hyperspectral imaging, devices, and systems are provided to enhance endoscopes with multiple wavelength capabilities and providing sequential imaging and display. A first optical device is provided for endoscopy imaging in a white light and a fluoresced light mode with an imaging unit including one or more image sensors. A mechanism in the first optical device to automatically adjust the focus of the first optical device using one or more deformable, variable-focus lenses, wherein the automatic focus adjustment compensates for a chromatic focal difference between the light collected at distinct wavelength bands caused by the dispersive or diffractive properties of the optical materials or optical design employed in the construction of the first or second optical devices, or both. Further variable spectrum imaging is enhanced with the use of adjustable spectral filters.

An observation condition acquisition unit acquires an observation condition including at least one of a moving speed of an endoscope, an observation distance between the endoscope and an observation target, or brightness of the observation target. A lesion information acquisition unit acquires lesion information including at least one of a diagnostic purpose or a certainty degree of a lesion obtained from an endoscope image at a timing at which the observation condition is acquired. A display format determination unit determines a display format of the lesion information on a display based on at least any of the observation condition or the lesion information. A control of displaying the lesion information on the display according to the display format is performed.

Disclosed herein are methods of vascular and structural imaging using imaging systems and methods described, the methods comprising producing an image of the vasculature or structure by imaging fluorescence using an imaging system, the system comprising: i) one or more detectors configured to form a fluorescence image of the sample and form a visible image of the sample; ii) a light source configured to emit an excitation light to induce fluorescence from the sample; and iii) a plurality of optics arranged to: direct the excitation light toward the sample; and direct a fluorescent light and a visible light from the sample to the detector; wherein the excitation light and the fluorescence light are directed substantially coaxially.

A system for polarimetric characterization of a target that includes a liquid light guide (LLG) for propagating light from a light source to the target (S) at least one of a Polarization State Analyzer (PSA) serving to analyze polarization of light having propagated into the LLG and that has been reflected by the target, and a Polarized State Generator (PSG) for modulating the polarization of light injected into the LLG, an optical detector for detecting light backscattered by the target (S) that has been illuminated by the LLG.

Provided is a medical display control device including a display control unit that causes a first captured medical image and a second captured medical image to be simultaneously displayed, the first captured medical image having been captured in an imaging device in a first imaging mode where imaging is performed with special light, the second captured medical image having been captured in the imaging device in a second imaging mode different from the first imaging mode before the first captured medical image.

An endoscope system includes: a processor that generates first and second feature amount distribution images of a living tissue from an imaged image of the living tissue and generates a second feature amount distribution processed image from these distribution images; and a display that displays the second feature amount distribution processed image. The processor generates a mask image of the second feature amount distribution image by, in the first feature amount distribution image, setting a pixel whose pixel value representing the first feature amount is less than a lower limit value as a non-transmissive pixel having a transmittance of zero and setting a pixel between an upper limit value and the lower limit value as a transmissive pixel while giving the pixel a transmittance determined continuously or stepwise in accordance with the pixel value in the first feature amount distribution image.