Pulsed fluorescence imaging in a light deficient environment is disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a controller configured to synchronize timing of the emitter and the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises electromagnetic radiation having a wavelength from about 795 nm to about 815 nm.

An image sensor includes: light receiving units disposed two-dimensionally on a substrate; color filters disposed on the light receiving units and including at least one of: a blue color filter for passing both of blue light and blue-violet light; a cyan color filter for passing both of green light and the blue-violet light; and a magenta color filter for passing both of red light and the blue-violet light; a first film arranged on a light receiving unit on which the cyan color filter is disposed, among the light receiving units, the first film having a peak of reflectivity near 450 nm; and a second film arranged on a light receiving unit on which the magenta color filter is disposed, among the light receiving units, the second film having a peak of reflectivity between 450 nm and 500 nm.

The invention discloses a visualization system with a real-time imaging function, comprising: a receiving end, a light source, an imaging system, and a display device. The light source comprises a red light source and a fluorescence excitation light source; the imaging system comprises a red light image sensor and a fluorescence image sensor to process a signal to output a real-time visualization signal to the display device. Through the technical scheme, the visualization system can provide sufficient background information and obtain a clear and complete real-time image for a surgeon only by using a specific band of red light to illuminate a surgical scene, the visualization system is simple in whole structure, is convenient in a control method, is simple and highly effective in the imaging process procedure, has a good use experience while the manufacturing and maintenance costs are low, and has a very high applicability and popularization.

There is provided a camera head for endoscope which enables to achieve a favorable fluorescent image in any wavelength band when the observation is switched over from a normal white-light image observation to an observation of fluorescent images of different wavelength bands.

The camera head for endoscope includes a camera-head optical system which includes a spectral prism having a dichroic film which splits light from the endoscope into white light and fluorescent light, and a first image pickup element and a second image pickup element which are disposed in respective optical paths split into two by the spectral prism, and the first image pickup element is for the white-light image observation in which a white-light image is captured, and the second image pickup element is for a fluorescent-image observation in which two fluorescent images of different wavelengths are captured, and the first image pickup element is disposed at a position at which an image is formed in an optical path for the white-light image observation, and the second image pickup element is disposed at a position between two positions at which the two fluorescent images are formed in an optical path for the fluorescent-mage observation, and the camera head for endoscope satisfies the following conditional expression (1).

d≦9×P×Fno  (1)

The present disclosure provides systems and methods for medical imaging. The system may comprise an optical adapter. The optical adapter may comprise a housing that comprises (1) a first end configured to releasably couple to a scope and (2) a second end configured to releasably couple to a camera. The optical adapter may comprise an image sensor coupled to the housing. The optical adapter may comprise an optics assembly disposed in the housing. The optics assembly may be configured to (1) receive light signals that are reflected from a target site within a subject's body and transmitted through the scope, and (2) reflect a first portion of the light signals onto the image sensor while permitting a second portion of the light signals to pass through to the camera.

Adaptive imaging methods and systems for generating enhanced low light video of an object for medical visualization are disclosed and include acquiring, with an image acquisition assembly, a sequence of reference frames and/or a sequence of low light video frames depicting the object, assessing relative movement between the image acquisition assembly and the object based on at least a portion of the acquired sequence of reference video frames or the acquired sequence of low light video frames, adjusting a level of image processing of the low light video frames based at least in part on the relative movement between the image acquisition assembly and the object, and generating a characteristic low light video output from a quantity of the low light video frames, wherein the quantity of the low light video frames is based on the adjusted level of image processing of the low light video frames.

An adaptor including: first and second optical systems; a prism comprising a mirror region, first light flux and second light flux from the respective optical systems, being incident on the prism, the light flux passing through the prism at a portion, the second light flux being reflected by a mirror region after passing through the portion, the light flux emitted from the prism to a region; and a light-shield at the region, the light-shield shields one of the first and second light flux and is disposed proximally to the prism relative to an imaging system of the endoscope when the adaptor is attached to an endoscope; the first optical system is disposed such that the first light flux is incident in a direction parallel to an optical axis, the second optical system is disposed so that the second light flux is incident in a direction orthogonal to the optical axis.

Pulsed fluorescence imaging in a light deficient environment is disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a controller configured to synchronize timing of the emitter and the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises electromagnetic radiation having a wavelength from about 770 nm to about 790 nm or from about 795 nm to about 815 nm.

An endoscopic imaging system for use in a light deficient environment includes an imaging device having a tube, one or more image sensors, and a lens assembly including at least one optical elements that corresponds to the one or more image sensors. The endoscopic system includes a display for a user to visualize a scene and an image signal processing controller. The endoscopic system includes a light engine having an illumination source generating one or more pulses of electromagnetic radiation and a lumen transmitting one or more pulses of electromagnetic radiation to a distal tip of an endoscope.

A stereo colposcope having variable linearity filter systems for both the excitation step and the suppression step, and can be used universally with any fluorescent compound or drug, as is the case of photodynamic diagnosis (PDD). The colposcope is a two-way colposcope because the treatment can be administered by an optical system or by a light-producing radio-frequency electrical current with a diathermic effect which facilitates photodynamic treatment. The colposcope produces ozone, which has an antiseptic effect when applied to the genital tract. A monitor provides for three-dimensional viewing through the use of two video cameras with the DLP (Digital Light Processing) and HDTV (High Definition Television) systems with the use of active lenses.