C07C211/49

MULTIFUNCTIONAL GROUP METAL CORROSION INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Provided is a multifunctional group metal corrosion inhibitor, as shown in one or more of formula (I-a) to formula (I-c). The metal corrosion inhibitor disclosure is a multifunctional group metal corrosion inhibitor comprising Schiff base or a derivative structure thereof, a catechol group and a mercapto group. A plurality of active functional groups are introduced, so that the active adsorption site of the inhibitor can be increased, and the synergetic effect of the three functional groups can enhance the adsorption effect of the inhibitor and a metal, And thus, the inhibitor is suitable for applicable for adsorptions of plurality of metals. Therefore, the inhibitor can exert a high anti-corrosion efficiency under the condition of a low addition amount, and provides a protection effect for the plurality of the metals.

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Tertiary amines for use in the treatment of cardiac disorders

The present invention relates to tertiary amines of formula (I) for use in therapy, particularly for use in treating cardiovascular disorders. The compounds have been found to regulate phospholamban phosphorylation by interfering with the A-kinase anchor protein 18delta (AKAP185) binding to the PKA substrate phospholamban. The compounds share a tri(alkylaryl/alkylheteroaryl)amine structure. ##STR00001##

Tertiary amines for use in the treatment of cardiac disorders

The present invention relates to tertiary amines of formula (I) for use in therapy, particularly for use in treating cardiovascular disorders. The compounds have been found to regulate phospholamban phosphorylation by interfering with the A-kinase anchor protein 18delta (AKAP185) binding to the PKA substrate phospholamban. The compounds share a tri(alkylaryl/alkylheteroaryl)amine structure. ##STR00001##

Palladium(II) complex for catalyzing sonogashira coupling reactions and a method thereof

A palladium(II) complex which catalyzes the Sonogashira coupling reaction efficiently under aerobic condition and a method of employing the palladium(II) complex to synthesize internal alkynes. The palladium(II) complex is an effective catalyst for the coupling reactions of aryl iodo and diiodo compounds with unactivated alkyl alkynes and terminal dialkynes to produce various novel symmetrical dialkynes and disubstituted internal alkynes in excellent yields.

Palladium(II) complex for catalyzing sonogashira coupling reactions and a method thereof

A palladium(II) complex which catalyzes the Sonogashira coupling reaction efficiently under aerobic condition and a method of employing the palladium(II) complex to synthesize internal alkynes. The palladium(II) complex is an effective catalyst for the coupling reactions of aryl iodo and diiodo compounds with unactivated alkyl alkynes and terminal dialkynes to produce various novel symmetrical dialkynes and disubstituted internal alkynes in excellent yields.

SYNTHESIS OF THERAPEUTIC AND DIAGNOSTIC DRUGS CENTERED ON REGIOSELECTIVE AND STEREOSELECTIVE RING OPENING OF AZIRIDINIUM IONS
20170008863 · 2017-01-12 ·

Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.

SYNTHESIS OF THERAPEUTIC AND DIAGNOSTIC DRUGS CENTERED ON REGIOSELECTIVE AND STEREOSELECTIVE RING OPENING OF AZIRIDINIUM IONS
20170008863 · 2017-01-12 ·

Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.

SMALL MOLECULE INHIBITORS OF ID PROTEINS
20250230124 · 2025-07-17 ·

The present technology relates generally to compounds, compositions, and methods useful for treating, preventing, and/or ameliorating pathogenic cellular proliferation, angiogenesis, cancer, metastatic disease, and/or a pathogenic vascular proliferative disease in a subject.

PROCESS FOR RECOVERING RAW MATERIALS FROM A POLYURETHANE MATERIAL

A process for recovering an amine substance from a polyurethane material, preferably from an end-of-life (eol) polyurethane material, is provided, wherein the process comprises alcoholising a polyurethane material by contacting the polyurethane material with an alcoholising substance, wherein water is added in an amount so that a water content of a resulting mixture is from about 0.2 eq. to about 30 eq., based on the amount of cleavable bonds in the polyurethane material, wherein during alcoholising of the polyurethane material an amine substance and a polyol substance is formed, allowing the mixture to settle, wherein a phase, in particular a first phase, which is polyol substance rich, and a phase, in particular a second phase, which is alcoholising substance rich, are formed and wherein the process comprises a work-up of the mixture by purification of the amine substance, including distilling the phase, which is alcoholising substance rich, in particular the second phase, in a first distillation, in order to purify the amine substance, wherein the first distillation includes one or more distillation stages.

PROCESS FOR RECOVERING RAW MATERIALS FROM A POLYURETHANE MATERIAL

A process for recovering an amine substance from a polyurethane material, preferably from an end-of-life (eol) polyurethane material, is provided, wherein the process comprises alcoholising a polyurethane material by contacting the polyurethane material with an alcoholising substance, wherein water is added in an amount so that a water content of a resulting mixture is from about 0.2 eq. to about 30 eq., based on the amount of cleavable bonds in the polyurethane material, wherein during alcoholising of the polyurethane material an amine substance and a polyol substance is formed, allowing the mixture to settle, wherein a phase, in particular a first phase, which is polyol substance rich, and a phase, in particular a second phase, which is alcoholising substance rich, are formed and wherein the process comprises a work-up of the mixture by purification of the amine substance, including distilling the phase, which is alcoholising substance rich, in particular the second phase, in a first distillation, in order to purify the amine substance, wherein the first distillation includes one or more distillation stages.