Disclosed are compounds that can modulate DDAH and the amount of asymmetric dimethylarginine (ADMA) in a subject. Also provided are pharmaceutical compositions comprising these compounds, as well as methods of using these compositions to treat and/or prevent diseases associated with elevated or low levels of DDAH and ADMA.

Disclosed are compounds that can modulate DDAH and the amount of asymmetric dimethylarginine (ADMA) in a subject. Also provided are pharmaceutical compositions comprising these compounds, as well as methods of using these compositions to treat and/or prevent diseases associated with elevated or low levels of DDAH and ADMA.

Disclosed are compounds that can modulate DDAH and the amount of asymmetric dimethylarginine (ADMA) in a subject. Also provided are pharmaceutical compositions comprising these compounds, as well as methods of using these compositions to treat and/or prevent diseases associated with elevated or low levels of DDAH and ADMA.

Disclosed are compounds that can modulate DDAH and the amount of asymmetric dimethylarginine (ADMA) in a subject. Also provided are pharmaceutical compositions comprising these compounds, as well as methods of using these compositions to treat and/or prevent diseases associated with elevated or low levels of DDAH and ADMA.

The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds.

Antidegradant compound of Formula I:

##STR00001##

and antidegradant composition comprising the same and rubber composition comprising the antidegradant compound or composition. The rubber composition has good resistance to appearance discoloration while maintaining the mechanical and anti-aging properties, thus, are suitable for making the entire tire or as part of the rubber matrix.

Antidegradant compound of Formula I:

##STR00001##

and antidegradant composition comprising the same and rubber composition comprising the antidegradant compound or composition. The rubber composition has good resistance to appearance discoloration while maintaining the mechanical and anti-aging properties, thus, are suitable for making the entire tire or as part of the rubber matrix.

A method for preparing an aryl substituted p-phenylenediamine substance is provided. A structural formula of the aryl substituted p-phenylenediamine substance is shown as Formula (I), where each of R and R is phenyl or o-methylphenyl, and R is same as or different from R; and the method comprises that: a raw material A and a raw material B are reacted in the presence of a hydrogen acceptor and a catalyst to form the aryl substituted p-phenylenediamine substance, the raw material A having a structure shown as Formula (I), the raw material B being cyclohexanone and/or o-methylcyclohexanone and the hydrogen acceptor being a hydrogen acceptor capable of accepting hydrogen for conversion into the raw material B. Raw materials are low in cost and readily available; use of a large amount of water for post-treatment is avoided. The reaction condition is relatively mild, and corrosion to equipment is avoided.

A method for preparing an aryl substituted p-phenylenediamine substance is provided. A structural formula of the aryl substituted p-phenylenediamine substance is shown as Formula (I), where each of R and R is phenyl or o-methylphenyl, and R is same as or different from R; and the method comprises that: a raw material A and a raw material B are reacted in the presence of a hydrogen acceptor and a catalyst to form the aryl substituted p-phenylenediamine substance, the raw material A having a structure shown as Formula (I), the raw material B being cyclohexanone and/or o-methylcyclohexanone and the hydrogen acceptor being a hydrogen acceptor capable of accepting hydrogen for conversion into the raw material B. Raw materials are low in cost and readily available; use of a large amount of water for post-treatment is avoided. The reaction condition is relatively mild, and corrosion to equipment is avoided.

Compositions of oligoanilines with higher purity, methods of making and using thereof, are provided. The compositions are produced in large scale with larger yield using simple purification techniques such as washing. Methods have been developed that allow large scale synthesis of oligoaniline compounds with the following benefits: (i) higher purity; (ii) larger yield of oligoaniline compounds; (iii) simple purification that does not require complicated techniques such as liquid chromatograph; (iv) lower cost; and (v) full characterization. The highly pure oligoaniline compositions can be used as reducing or oxidizing agent in a redox reaction. The oligoaniline compositions have colors and can be used as dyes, i.e. redox active dyes in a redox reaction, as intermediates for the development of conductive elastomers, or as catalysts.