The present disclosure describes an L-S2-amino-4-halobutyric acid derivative-L-tartrate salt. The present disclosure also describes a method of preparing L-S-amino-4-halobutyric acid derivative-L-tartrate salt, comprising the following steps: using D, L-S2-amino-4-halobutyric acid derivative enantiomeric mixture as the raw material, using L-tartrate as the resolution agent, and obtaining L-S2-Amino-4-halobutyric acid derivative-L-tartrate by resolution reaction, crystallization and filtration in the same resolution agent system; or the enantiomeric mixture of D, L-S2-amino-4-halobutyric acid derivatives is used as raw material, L-tartrate is used as resolution agent under aromatic aldehyde catalysis or aromatic aldehyde and organic acid co-catalysis, and dynamic resolution reaction is carried out in the same resolution agent system, further comprising crystallization and filtration to obtain L-S2-amino-4-halobutyric acid derivative-L-tartrate.

Compounds provided herein function as thyromimetics and have utility for treating diseases such as neurodegenerative disorders and fibrotic diseases. Pharmaceutical compositions containing such compounds are also provided, as are methods of their preparation.

Compounds provided herein function as thyromimetics and have utility for treating diseases such as neurodegenerative disorders and fibrotic diseases. Pharmaceutical compositions containing such compounds are also provided, as are methods of their preparation.

The present invention provides compounds, compositions thereof, and methods of using the same.

The present invention provides compounds, compositions thereof, and methods of using the same.