The invention discloses a method for fluoroalkylation of enamines with a fluoro alkyl halide in the presence of a base.

The invention discloses a method for fluoroalkylation of enamines with a fluoro alkyl halide in the presence of a base.

Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.

The present invention relates to compounds of Formula (I), wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4x, R.sup.4y, m, n and G are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controlling weeds, in particular in crops of useful plants.

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The present invention relates to compounds of Formula (I), wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4x, R.sup.4y, m, n and G are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controlling weeds, in particular in crops of useful plants.

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Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.

The present invention provides a method for synthesizing a carboxy-containing anthraquinone derivative, including the following steps: S1, mixing a terminal carboxy-containing dibasic acid with thionyl chloride, and adding toluene as a reaction solvent, followed by adding a catalyst and heating to a predetermined temperature for a reaction; S2, after the reaction is completed, removing the reaction solvent and the thionyl chloride, followed by adding toluene for distillation, to obtain a reactant; S3, mixing the reactant with aminoanthraquinone, adding toluene as a reaction solvent, followed by heating to reflux for a reaction; and S4, after the reaction is completed, removing the reaction solvent, adding a potassium carbonate solution to the residue, filtering it to remove a solid, adjusting the filtrate to a predetermined pH value to precipitate a solid, followed by filtering out, washing, and drying the precipitated solid, to obtain the carboxy-containing anthraquinone derivative.

The present invention provides a method for synthesizing a carboxy-containing anthraquinone derivative, including the following steps: S1, mixing a terminal carboxy-containing dibasic acid with thionyl chloride, and adding toluene as a reaction solvent, followed by adding a catalyst and heating to a predetermined temperature for a reaction; S2, after the reaction is completed, removing the reaction solvent and the thionyl chloride, followed by adding toluene for distillation, to obtain a reactant; S3, mixing the reactant with aminoanthraquinone, adding toluene as a reaction solvent, followed by heating to reflux for a reaction; and S4, after the reaction is completed, removing the reaction solvent, adding a potassium carbonate solution to the residue, filtering it to remove a solid, adjusting the filtrate to a predetermined pH value to precipitate a solid, followed by filtering out, washing, and drying the precipitated solid, to obtain the carboxy-containing anthraquinone derivative.

The present invention relates to an aromatic compound and a preparation method therefor and the use thereof. Specifically, disclosed are a compound as shown in the following general formula (I), or a tautomer, an enantiomer, a diastereomer or a racemate thereof or a mixture thereof, or a pharmaceutically acceptable salt thereof. Also disclosed are a method for preparing the above compound and the use of same in the treatment of nervous system diseases.

Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.