Compounds represented by the formula ##STR00001## and their edible salts, and edible compositions containing same wherein R.sub.1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, such that R.sub.1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and the amino acid residue connected to the carbonyl carbon atom is a residue of a 1-amino cycloalkane carboxylic acid (ACCA), and n is 1, 2, 3 or 4.

Compounds represented by the formula ##STR00001## and their edible salts, and edible compositions containing same wherein R.sub.1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, such that R.sub.1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and the amino acid residue connected to the carbonyl carbon atom is a residue of a 1-amino cycloalkane carboxylic acid (ACCA), and n is 1, 2, 3 or 4.

An oseltamivir analogue and nanoparticles having the analogue bound thereto, of the present invention, strongly bind to oseltamivir-resistant influenza virus, and thus, the use of the same can allow detection of oseltamivir-resistant influenza viruses quickly and conveniently with the naked eye. Therefore, the present invention can be favorably utilized in promptly establishing a therapeutic schedule for a patient infected with influenza viruses.

An oseltamivir analogue and nanoparticles having the analogue bound thereto, of the present invention, strongly bind to oseltamivir-resistant influenza virus, and thus, the use of the same can allow detection of oseltamivir-resistant influenza viruses quickly and conveniently with the naked eye. Therefore, the present invention can be favorably utilized in promptly establishing a therapeutic schedule for a patient infected with influenza viruses.

The present invention relates to a novel process for preparing substituted cyclohexane amino acid esters and spiroketal-substituted cyclic keto-enols, and to novel intermediates or starting compounds that are passed through or used in the process according to the invention.

The present invention relates to a novel process for preparing substituted cyclohexane amino acid esters and spiroketal-substituted cyclic keto-enols, and to novel intermediates or starting compounds that are passed through or used in the process according to the invention.

Shown is a compound represented by formula (1). For example, R.sup.1 is alkyl having 1 to 15 carbons; MES is a mesogen group having at least one ring; Sp.sup.1 is a single bond or alkylene having 1 to 10 carbons; M.sup.1 is methyl; and R.sup.2, M.sup.2 and M.sup.3 are hydrogen.

##STR00001##

The present invention provides a polymerizable compound denoted by Formula (I): in the formula, Z.sup.1 and Z.sup.2 represent an arylene group, and the like, m represents 1 or 2, n represents an integer of 0 or 1, and when m is 2, n is 0, L.sup.1, L.sup.2, L.sup.3, and L.sup.4 each independently represent a linking group such as C(O)O and OC(O), T.sup.3 represents -Sp.sup.4-R.sup.4, X represents O, and the like, r represents 1 to 4, Sp.sup.1, Sp.sup.2, Sp.sup.3, Sp.sup.4, and Sp.sup.5 each independently represent a single bond or a linking group, R.sup.1 and R.sup.2 each independently represent a polymerizable group, and R.sup.3, R.sup.4, and R.sup.5 each independently represent a hydrogen atom, a polymerizable group, or the like; a polymerizable composition containing the polymerizable compound described above; a film formed of the polymerizable composition described above; and a half mirror for displaying a projection image including the film described above. ##STR00001##

The present invention provides a polymerizable compound denoted by Formula (I): in the formula, Z.sup.1 and Z.sup.2 represent an arylene group, and the like, m represents 1 or 2, n represents an integer of 0 or 1, and when m is 2, n is 0, L.sup.1, L.sup.2, L.sup.3, and L.sup.4 each independently represent a linking group such as C(O)O and OC(O), T.sup.3 represents -Sp.sup.4-R.sup.4, X represents O, and the like, r represents 1 to 4, Sp.sup.1, Sp.sup.2, Sp.sup.3, Sp.sup.4, and Sp.sup.5 each independently represent a single bond or a linking group, R.sup.1 and R.sup.2 each independently represent a polymerizable group, and R.sup.3, R.sup.4, and R.sup.5 each independently represent a hydrogen atom, a polymerizable group, or the like; a polymerizable composition containing the polymerizable compound described above; a film formed of the polymerizable composition described above; and a half mirror for displaying a projection image including the film described above. ##STR00001##

Analgesic compounds for treatment of pain or fever that include a bicyclopentane moiety linked to an amine, combinations of the compounds with opioid analgesic drugs, and methods for treating pain or fever by administering a compound described herein.