A process for making certain spiroheterocyclic pyrrolidine dione derivatives.

A process for making certain spiroheterocyclic pyrrolidine dione derivatives.

Described herein are methods of oxidative coupling of aryl boron reagents with sp.sup.3-carbon nucleophiles, and ambient decarboxylative arylation of malonate half-esters via oxidative catalysis.

Described herein are methods of oxidative coupling of aryl boron reagents with sp.sup.3-carbon nucleophiles, and ambient decarboxylative arylation of malonate half-esters via oxidative catalysis.

A process for making certain spiroheterocyclic pyrrolidine dione derivatives.

A process for making certain spiroheterocyclic pyrrolidine dione derivatives.

An organic electroluminescent device having a capping layer composed of material having a high refractive index that involves only small differences in refractive indices measured in the blue, green, and red wavelength regions, excelling in thin film stability and durability and having no absorption in the respective wavelength ranges of blue, green, and red is provided to improve device characteristics of the organic electroluminescent device, particularly to greatly improve the coupling-out efficiency. The organic electroluminescent device includes at least an anode, a hole transport layer, a light emitting layer, an electron transport layer, a cathode, and a capping layer in this order, wherein the capping layer contains a phthalic acid derivative represented by the following general formula ##STR00001##

An organic electroluminescent device having a capping layer composed of material having a high refractive index that involves only small differences in refractive indices measured in the blue, green, and red wavelength regions, excelling in thin film stability and durability and having no absorption in the respective wavelength ranges of blue, green, and red is provided to improve device characteristics of the organic electroluminescent device, particularly to greatly improve the coupling-out efficiency. The organic electroluminescent device includes at least an anode, a hole transport layer, a light emitting layer, an electron transport layer, a cathode, and a capping layer in this order, wherein the capping layer contains a phthalic acid derivative represented by the following general formula ##STR00001##

Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.

Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.