In general, devices, systems, and methods for multi-source imaging are provided.

Systems, devices and methods for imaging hard-to-view and hard-to-reach places in the oral cavity, such as at the base of the tongue and tonsillar regions, are described. An example mobile intraoral imaging system includes a white light source and a blue or ultraviolet light source for illuminating a region in the oral cavity. The system includes a mobile device configured to receive information associated with reflected and autofluorescent light from the region in the oral cavity, as well as a semi-flexible probe that includes a bendable tip; the probe is changeable in shape to allow insertion in the oral cavity and includes a camera that is positioned at a section of its tip to capture the reflected and autofluorescent light. The system enables quick acquisition of high-quality images, and allows remote imaging and diagnosis of suspicious lesions in the oral cavity.

The present invention provides a system for extension of dynamic range and contrast of a video capture under fluorescence imaging conditions using a single detector. For this purpose, the system (100) comprises of a light engine (107) which sequentially switches between a high-intensity fluorescence excitation light mode (107A), a low-intensity fluorescence excitation light mode (107B) and NIR reflectance light (107C). Correspondingly, a detector (103) captures three data streams—High Intensity Fluorescence Data (105A), Low Intensity Fluorescence Data (105B) and NIR Reflectance Data (105D). A scene processing unit (105) then processes the three data streams and generate two additional data streams—a Wide Dynamic Range Fluorescence Data Stream (105C) and an Enhanced Vascular Index Data Stream (105E). The system also uses a Selective Visualization Unit (106) to allow the user to visualize any of five data streams.

To simplify the use of a functional scope of a medical image recording system, for example an endoscopy system, a method is proposed in which an image processing unit of the image recording system recognizes predefined image recording situations on the basis of an image sequence recorded using an image sensor of the image recording system and in response thereto proposes an adaptation to a user that results in an improved display and/or an improved recording of the image sequence in the respective recognized image recording situation. The adaptation can relate here to an algorithm, using which the image sequence is processed after the recording, and/or an image recording method currently used to generate the image sequence.

Pulsed hyperspectral, fluorescence, and laser mapping imaging without input clock or data transmission clock is disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a plurality of bidirectional data pads and a controller in communication with the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises one or more of: electromagnetic radiation having a wavelength from about 513 nm to about 545 nm, from about 565 nm to about 585 nm, from about 900 nm to about 1000 nm, an excitation wavelength of electromagnetic radiation that causes a reagent to fluoresce, or a laser mapping pattern.

The disclosed apparatus, systems and methods relate to the use of optical nanoparticles in the illumination and imaging of tissues such as cancer tissues. Optical nanoparticles such as upconverting nanoparticles can be introduced into a patient and illuminated at a first time and wavelength and then imaged at a second time and wavelength to improve resolution and reduce imager size.

An endoscope includes a handle operation unit. The handle operation unit includes: an outer ring; a cam ring accommodated in the outer ring to rotate in accordance with rotation of the outer ring about a central axis and having a pair of guide holes; a pair of slide members accommodated in the respective guide holes and fixed to a force transmission member; and a support portion having a pair of slide grooves extending along a longitudinal direction of the endoscope, the support portion being accommodated in the cam ring to support the pair of slide members. The slide members slide in the respective slide grooves in accordance with the rotation of the outer ring. The field of view of the image-capturing unit is changed in accordance with sliding of the pair of slide members.

Fabrication processing is executed in a chip of an image sensor. An image capturing device includes an image capturing unit (11) mounted on a vehicle and configured to generate image data by performing image capturing of a peripheral region of the vehicle, a scene recognition unit (214) configured to recognize a scene of the peripheral region based on the image data, and a drive control unit (12) configured to control drive of the image capturing unit based on the scene recognized by the scene recognition unit.

Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed. An imaging device may include a housing having a first channel and a light guide disposed at least partially in the first channel. The imaging device may also include a clamp disposed in the housing, where the clamp is configured to apply a force to a rigid exterior portion of the light guide in a clamp direction transverse to the light guide longitudinal axis to secure the light guide to the housing. The clamp may have a clamp longitudinal axis parallel to a light guide longitudinal axis.

A method of imaging tissue of a subject using an electronic rolling shutter imager includes sequentially resetting rows of pixels of the rolling shutter imager from a first row to a last row, sequentially reading charge accumulated at the rows of pixels from the first row to the last row, wherein the first row is read after resetting the last row, illuminating the tissue of the subject with illumination light for an illumination period that lasts longer than a vertical blanking period, wherein the vertical blanking period is the period from the resetting of the last row to the reading of the first row, and generating an image frame from the readings of charge accumulated at the rows of pixels, wherein at least one reading of charge accumulated at a row of pixels is removed or replaced to generate the image frame.