Patent classifications
C07C237/12
COMPOSITIONS AND METHODS RELATING TO SALTS OF SPECIALIZED PRO-RESOLVING MEDIATORS
The present invention relates to compounds of Formulas I-IV, which are salts of special lipid mediators of inflammation, compositions containing same, and methods of using same in the treatment of various diseases and disorders characterized by chronic or excessive inflammation, or both. Provided are pharmaceutical compositions adapted to deliver the compounds the lower gastrointestinal tract and methods of using same as monotherapy in the treatment of inflammatory diseases or disorders of the lower gastrointestinal tract, and in combination therapy with 5-aminosalicylate.
Caspase inhibitor and pharmaceutical composition, use and therapeutic method thereof
Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases. ##STR00001##
Caspase inhibitor and pharmaceutical composition, use and therapeutic method thereof
Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases. ##STR00001##
Method for preparing novel crystalline forms of 1-(4-benzyloxy-benzyl)-3-methyl-thiourea
The present disclosure relates to a method for preparing 1-(4-benzyloxy-benzyl)-3-methyl-thiourea and a method for preparing a novel stable crystalline form A of 1-(4-benzyloxy-benzyl)-3-methyl-thiourea.
MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF
The present invention provides compounds, compositions thereof, and methods of using the same.
MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF
The present invention provides compounds, compositions thereof, and methods of using the same.
VEGETABLE OIL-BASED MATERIAL AS A SUBSTITUTE FOR CARNAUBA WAX
This invention relates to a wax composition comprising a plurality of fatty acid amide compounds having the Formula (I):
##STR00001##
where R.sup.1, R.sup.2, n.sub.1, n.sub.2, m.sub.1, and m.sub.2 are as described herein. This invention also relates to a wax composition comprising: a) one or more fatty acid amide compounds having the Formula (II):
##STR00002##
and b) one or more fatty acid amide compounds having the Formula (III):
##STR00003##
where R.sup.1, R.sup.2, n.sub.1, and n.sub.2 are as described herein. This invention also relates to a fatty acid amide compound having the Formula (I) and a process for preparing a compound of Formula (I).
VEGETABLE OIL-BASED MATERIAL AS A SUBSTITUTE FOR CARNAUBA WAX
This invention relates to a wax composition comprising a plurality of fatty acid amide compounds having the Formula (I):
##STR00001##
where R.sup.1, R.sup.2, n.sub.1, n.sub.2, m.sub.1, and m.sub.2 are as described herein. This invention also relates to a wax composition comprising: a) one or more fatty acid amide compounds having the Formula (II):
##STR00002##
and b) one or more fatty acid amide compounds having the Formula (III):
##STR00003##
where R.sup.1, R.sup.2, n.sub.1, and n.sub.2 are as described herein. This invention also relates to a fatty acid amide compound having the Formula (I) and a process for preparing a compound of Formula (I).
Solid Support
A solid support for use in non-aqueous DNA-conjugated molecule reactions, wherein the support comprises a solid body formed from a plurality of polyethylene glycol units, wherein the solid body includes at least one cationic moiety.
Solid Support
A solid support for use in non-aqueous DNA-conjugated molecule reactions, wherein the support comprises a solid body formed from a plurality of polyethylene glycol units, wherein the solid body includes at least one cationic moiety.