C07C251/54

Acetophenone oxime compound and application thereof

Disclosed are an acetophenone oxime compound and a preparation method therefor, and specifically disclosed are a compound as shown in formula (II) and a pharmaceutically acceptable salt thereof. ##STR00001##

2,6-DIBENZYLIDENECYCLOHEXANONE OXIME COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF

A 2,6-dibenzylidenecyclohexanone oxime compound and a preparation method and use thereof are provided. A structural fragment with anti-inflammatory activity is introduced into the 2,6-dibenzylidenecyclohexanone oxime compound, and the prepared compound has stable physicochemical properties. The 2,6-dibenzylidenecyclohexanone oxime compound has an excellent inhibitory effect on inflammatory factors and better in-vivo anti-inflammatory activity, and especially has a protective effect on hepatitis and fatty liver caused by excessive expression and release of TNF- and/or IL-6, as well as liver inflammation and liver lipid metabolism.

2,6-DIBENZYLIDENECYCLOHEXANONE OXIME COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF

A 2,6-dibenzylidenecyclohexanone oxime compound and a preparation method and use thereof are provided. A structural fragment with anti-inflammatory activity is introduced into the 2,6-dibenzylidenecyclohexanone oxime compound, and the prepared compound has stable physicochemical properties. The 2,6-dibenzylidenecyclohexanone oxime compound has an excellent inhibitory effect on inflammatory factors and better in-vivo anti-inflammatory activity, and especially has a protective effect on hepatitis and fatty liver caused by excessive expression and release of TNF- and/or IL-6, as well as liver inflammation and liver lipid metabolism.