Embodiments described herein provide a compound that may be used in a variety of applications such as corrosion inhibition, additives for metalworking, mining reagents, epoxy curatives, emulsifiers, fuel or lubricant additives, surfactant manufacture, acid scavengers and asphalt additives. The compound has the following structure:

##STR00001##

where R.sub.1 is a methoxy group,
R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are independently a hydrogen atom or an alkyl group, and
R.sub.6 is an aminomethyl group.

Embodiments described herein provide a compound that may be used in a variety of applications such as corrosion inhibition, additives for metalworking, mining reagents, epoxy curatives, emulsifiers, fuel or lubricant additives, surfactant manufacture, acid scavengers and asphalt additives. The compound has the following structure:

##STR00001##

where R.sub.1 is a methoxy group,
R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are independently a hydrogen atom or an alkyl group, and
R.sub.6 is an aminomethyl group.

The invention relates to the use of a compound of formula (I)

##STR00001##

or a salt thereof for combating animal pests,
where the symbols and indices are defined in the specification.

The invention relates to the use of a compound of formula (I)

##STR00001##

or a salt thereof for combating animal pests,
where the symbols and indices are defined in the specification.

Embodiments described herein provide a compound that may be used in a variety of applications such as corrosion inhibition, additives for metalworking, mining reagents, epoxy curatives, emulsifiers, fuel or lubricant additives, surfactant manufacture, acid scavengers and asphalt additives. The compound has the following structure: ##STR00001## where R.sub.1 is a methoxy group, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are independently a hydrogen atom or an alkyl group, and R.sub.6 is an aminomethyl group.

Embodiments described herein provide a compound that may be used in a variety of applications such as corrosion inhibition, additives for metalworking, mining reagents, epoxy curatives, emulsifiers, fuel or lubricant additives, surfactant manufacture, acid scavengers and asphalt additives. The compound has the following structure: ##STR00001## where R.sub.1 is a methoxy group, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are independently a hydrogen atom or an alkyl group, and R.sub.6 is an aminomethyl group.

The invention relates to improved method of synthesis for Treprostinil comprising condensation reaction of the carbonyl compound having allyl, alkyl, crotyl or MEM-protected phenolic hydroxyl group, compound (4) with a hydroxyl-protected alkynol (5) to give the condensation product, compound (6). Subjecting compound (6) to oxidation, reduction, hydroxyl protection and carbonylation, cyclization reactions gave the tricyclic derivative (10). Further reactions comprising reduction, hydrogenation and deprotection of the phenolic and side-chain hydroxyl groups, wherein the sequence and choice of reagents was governed by protecting groups, gave the triol intermediate, compound (14). Cyanoalkylation at phenolic hydroxyl functionality and further hydrolysis yielded the prostacyclin compound, Treprostinil (1) and its pharmaceutically acceptable salts, having desired purity.

The invention relates to improved method of synthesis for Treprostinil comprising condensation reaction of the carbonyl compound having allyl, alkyl, crotyl or MEM-protected phenolic hydroxyl group, compound (4) with a hydroxyl-protected alkynol (5) to give the condensation product, compound (6). Subjecting compound (6) to oxidation, reduction, hydroxyl protection and carbonylation, cyclization reactions gave the tricyclic derivative (10). Further reactions comprising reduction, hydrogenation and deprotection of the phenolic and side-chain hydroxyl groups, wherein the sequence and choice of reagents was governed by protecting groups, gave the triol intermediate, compound (14). Cyanoalkylation at phenolic hydroxyl functionality and further hydrolysis yielded the prostacyclin compound, Treprostinil (1) and its pharmaceutically acceptable salts, having desired purity.

Methods of converting a fluorinated vinyl ether to a saturated partially fluorinated ether, the method comprising: reacting the fluorinated vinyl ether with an amine, ammonia, or combination thereof to form the saturated partially fluorinated ether.

Methods of converting a fluorinated vinyl ether to a saturated partially fluorinated ether, the method comprising: reacting the fluorinated vinyl ether with an amine, ammonia, or combination thereof to form the saturated partially fluorinated ether.