Compounds and compositions are provided that can inhibit microsomal prostaglandin E synthase-1 (mPGES-1). The compounds and compositions can reduce inflammation in a subject, such as inflammation caused by an inflammation disorder or symptoms thereof. Pharmaceutical compositions comprising the compound are also provided. Furthermore, methods are provided for reducing inflammation and/or inhibiting mPGES-1. The methods can comprise administering an effective amount of the composition to a subject.

The present invention relates to the provision of an organic compound or compounds containing a fluorenone derivative structure or its substituted derivatives to enhance the thermal stability of organic solar cells.

The present invention relates to the provision of an organic compound or compounds containing a fluorenone derivative structure or its substituted derivatives to enhance the thermal stability of organic solar cells.

A blue light blocking system including a pyrazoline compound of formula (I) or/and a phenylacrylic compound of formula (II) is provided. The compound of formula (I) or formula (II) can absorb most blue light of shorter wavelength that hurt eyes, but let that of the longer wavelength pass through, so that the transmitted light makes an excellent visual effect for human. The system can be applied to products such as optical films, optical lenses, goggles, skin care, lighting, coatings, adhesives, or panels. These products have a light-colored appearance and their transmitted light makes for an excellent visual effect.

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A blue light blocking system including a pyrazoline compound of formula (I) or/and a phenylacrylic compound of formula (II) is provided. The compound of formula (I) or formula (II) can absorb most blue light of shorter wavelength that hurt eyes, but let that of the longer wavelength pass through, so that the transmitted light makes an excellent visual effect for human. The system can be applied to products such as optical films, optical lenses, goggles, skin care, lighting, coatings, adhesives, or panels. These products have a light-colored appearance and their transmitted light makes for an excellent visual effect.

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The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.

A method of quenching excited state energy from a photodegradable pigment that has been excited by absorption of light having a wavelength in the wavelength range of 290-800 nm, comprising reacting a pigment with a conjugated fused tricyclic compound having electron withdrawing groups of Formula (II) or a salt thereof: ##STR00001## wherein: A is selected from the group consisting of O, S, CO, CS, ##STR00002## B.sup.1, B.sup.2, D.sup.1 and D.sup.2 are each independently selected from the group consisting of F, Cl, Br, I, CF.sub.3, CC13, NR33+, NO2, CN, C(O)R4, C(O)OR, SO2R5, aryl, and CCHR6; each m independently is 0, 1, 2, 3, or 4; a is 0 or 1; each R is independently selected from the group consisting of LI, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl; R.sup.2 is selected from the group consisting of H, alkyl, cycloalkyl, alkenyl, alkynyl, and aryl; each R.sup.3 is independently selected from the group consisting of H and C.sub.1-C.sub.6 alkyl; each R.sup.4 is independently selected from the group consisting of H, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl; each R.sup.5 is independently selected from the group consisting of H, O, OH, NH.sub.2, and Cl; and each R.sup.6 is-independently selected from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl.

A method of quenching excited state energy from a photodegradable pigment that has been excited by absorption of light having a wavelength in the wavelength range of 290-800 nm, comprising reacting a pigment with a conjugated fused tricyclic compound having electron withdrawing groups of Formula (II) or a salt thereof: ##STR00001## wherein: A is selected from the group consisting of O, S, CO, CS, ##STR00002## B.sup.1, B.sup.2, D.sup.1 and D.sup.2 are each independently selected from the group consisting of F, Cl, Br, I, CF.sub.3, CC13, NR33+, NO2, CN, C(O)R4, C(O)OR, SO2R5, aryl, and CCHR6; each m independently is 0, 1, 2, 3, or 4; a is 0 or 1; each R is independently selected from the group consisting of LI, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl; R.sup.2 is selected from the group consisting of H, alkyl, cycloalkyl, alkenyl, alkynyl, and aryl; each R.sup.3 is independently selected from the group consisting of H and C.sub.1-C.sub.6 alkyl; each R.sup.4 is independently selected from the group consisting of H, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl; each R.sup.5 is independently selected from the group consisting of H, O, OH, NH.sub.2, and Cl; and each R.sup.6 is-independently selected from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl.

An organic electroluminescence device including: an anode; a cathode; two or more emitting units that are disposed between the anode and the cathode, each unit having an emitting layer; and a charge-generating layer that is disposed between the emitting units, wherein the charge-generating layer includes an N layer nearer to the anode and a P layer nearer to the cathode, and the N layer includes a compound represented by the following formula (I) or (II): ##STR00001##

An organic electroluminescence device including: an anode; a cathode; two or more emitting units that are disposed between the anode and the cathode, each unit having an emitting layer; and a charge-generating layer that is disposed between the emitting units, wherein the charge-generating layer includes an N layer nearer to the anode and a P layer nearer to the cathode, and the N layer includes a compound represented by the following formula (I) or (II): ##STR00001##