Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.

The present invention is directed to compounds of the formula (I) wherein all substituents are defined herein, as well as pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

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The present invention is directed to compounds of the formula (I) wherein all substituents are defined herein, as well as pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

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This invention is directed to substituted acylanilide compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, a muscle wasting disease and/or disorder such as Duchenne muscular dystrophy or Becker muscular dystrophy.

This invention is directed to substituted acylanilide compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, a muscle wasting disease and/or disorder such as Duchenne muscular dystrophy or Becker muscular dystrophy.

The present invention relates to solid forms of (S)—N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide and process for producing the same.

Disclosed are compounds of formula (I) which possess anthelminthic properties wherein the structural elements have the meaning as indicated in the description. Further disclosed are such compounds for the control, treatment and/or prevention of infections with helminths in animals and humans.

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Disclosed are compounds of formula (I) which possess anthelminthic properties wherein the structural elements have the meaning as indicated in the description. Further disclosed are such compounds for the control, treatment and/or prevention of infections with helminths in animals and humans.

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An amide derivative represented by the following Formula (1) is provided as an amide derivative showing a significantly excellent effect for a pest control action. In the following Formula (1), A represents a carbon atom, a nitrogen atom, or the like, and K represents a non-metal atomic group necessary for forming a cyclic linking group derived from benzene or a heterocyclic. X represents a halogen atom or the like; n represents an integer of from 0 to 4. R.sub.1 and R.sub.2 represent hydrogen atoms, alkyl groups, or the like. T represents —C(=G.sub.1)-Q.sub.1 or —C(=G.sub.1)-G.sub.2Q.sub.2, and G.sub.1 to G.sub.3 each represent oxygen atoms or the like. Q.sub.1 and Q.sub.2 each represent a hydrogen atom, an alkyl group, an aryl group, or the like. Y.sub.1 and Y.sub.5 each represent a halogen atom or the like, Y.sub.2 and Y.sub.4 each represent a hydrogen atom or the like, and Y.sub.3 represents a C2-C5 haloalkyl group. ##STR00001##

An amide derivative represented by the following Formula (1) is provided as an amide derivative showing a significantly excellent effect for a pest control action. In the following Formula (1), A represents a carbon atom, a nitrogen atom, or the like, and K represents a non-metal atomic group necessary for forming a cyclic linking group derived from benzene or a heterocyclic. X represents a halogen atom or the like; n represents an integer of from 0 to 4. R.sub.1 and R.sub.2 represent hydrogen atoms, alkyl groups, or the like. T represents —C(=G.sub.1)-Q.sub.1 or —C(=G.sub.1)-G.sub.2Q.sub.2, and G.sub.1 to G.sub.3 each represent oxygen atoms or the like. Q.sub.1 and Q.sub.2 each represent a hydrogen atom, an alkyl group, an aryl group, or the like. Y.sub.1 and Y.sub.5 each represent a halogen atom or the like, Y.sub.2 and Y.sub.4 each represent a hydrogen atom or the like, and Y.sub.3 represents a C2-C5 haloalkyl group. ##STR00001##