Patent classifications
C07C271/10
SYNTHETIC METHOD AND SYNTHETIC SYSTEM
Provided is a synthesis method comprising a first step of producing a carbonate compound from carbon monoxide and an alcohol-based compound at an anode of a first electrochemical cell comprising a cathode and the anode, and a second step of synthesizing a first product by a dealcoholization reaction of the carbonate compound, wherein an alcohol-based compound eliminated in the second step is recycled in the first step.
Ingenol analogs, pharmaceutical compositions and methods of use thereof
The invention relates to compounds of Formula (I), (II), (III) or (IV), salts thereof, pharmaceutical compositions thereof, as well as methods of treating, curing or preventing HIV in subjects.
Carbamate ester compound and acrylic rubber composition containing the same
A carbamate ester compound represented by the general formula:
ZOCONH(CH.sub.2).sub.nNHCOOZ[I]
wherein Z is [i], [ii], or [iii] below, and n is an integer of 2 to 10, ##STR00001## (wherein R.sup.1 and R.sup.2 are each independently a lower alkyl group having 1 to 5 carbon atoms, R.sup.3 is a hydrogen atom or a lower alkyl group having 1 to 5 carbon atoms, and a is 1 or 2). The carbamate ester compound is used as a vulcanizing agent for carboxyl group-containing acrylic rubber and improves the delay of the vulcanization rate by scorch suppression.
Carbamate ester compound and acrylic rubber composition containing the same
A carbamate ester compound represented by the general formula:
ZOCONH(CH.sub.2).sub.nNHCOOZ[I]
wherein Z is [i], [ii], or [iii] below, and n is an integer of 2 to 10, ##STR00001## (wherein R.sup.1 and R.sup.2 are each independently a lower alkyl group having 1 to 5 carbon atoms, R.sup.3 is a hydrogen atom or a lower alkyl group having 1 to 5 carbon atoms, and a is 1 or 2). The carbamate ester compound is used as a vulcanizing agent for carboxyl group-containing acrylic rubber and improves the delay of the vulcanization rate by scorch suppression.
Process to produce polycarbamate, polycarbamate produced thereby and a coating composition comprising the polycarbamate
A polycarbamate comprising having less than 5 wt % total of biuret, cyanuric acid, and polyallophanate; and has a Gardner level of equal or greater than 3 is provided. A coating comprising the polycarbamate is also provided.
Process to produce polycarbamate, polycarbamate produced thereby and a coating composition comprising the polycarbamate
A polycarbamate comprising having less than 5 wt % total of biuret, cyanuric acid, and polyallophanate; and has a Gardner level of equal or greater than 3 is provided. A coating comprising the polycarbamate is also provided.
Carbamate compounds and methods of making and using same
This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for method of treating a patient in need thereof, where the patient is suffering from post-traumatic stress disorder comprising administering a disclosed compound or composition.
Carbamate compounds and methods of making and using same
This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for method of treating a patient in need thereof, where the patient is suffering from post-traumatic stress disorder comprising administering a disclosed compound or composition.
Fused cyclooctyne compounds and their use in metal-free click reactions
The invention relates to fused cyclooctyne compounds, and to a method for their preparation. The invention also relates to a conjugate wherein a fused cyclooctyne compound according to the invention is conjugated to a label, and to the use of these conjugates in bioorthogonal labeling, imaging and/or modification, such as for example surface modification, of a target molecule. The invention further relates to a method for the modification of a target molecule, wherein a conjugate according to the invention is reacted with a compound comprising a 1,3-dipole or a 1,3-(hetero)diene.
INGENOL ANALOGS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF
The invention relates to compounds of Formula (I), (II), (III) or (IV), salts thereof, pharmaceutical compositions thereof, as well as methods of treating, curing or preventing HIV in subjects.