Methods for quantifying fluorescence and optical properties in a turbid medium such as tissue. Devices and systems suitable for the methods are also disclosed.

A stereo-endoscope for observation and analysis of an object, comprising a shaft with distal and proximal ends, illuminating means for illuminating the object, and stereoscopic imaging means which transfer light radiated by the object from the distal end to the proximal end. Light of a first imaging channel is fed into a first sensor, and light of a second imaging channel is fed into a second sensor. Both sensors contain mutually different beam splitters, which split the light into four light beams. One light beam from each of the sensors is deflected onto one sensor each; these two sensors are identical. The signals detected there are assembled to form a stereoscopic image. The stereo-endoscope comprises mutually different manipulating means for the other two light beams; by means of suitably-tuned image-processing algorithms, two different monoscopic images containing information complementary to each other and to the stereoscopic image are generated.

Provided are medical imaging apparatuses that comprising an optical connector, a coupler configured to releasably couple to a first portion of the optical connector and a camera configured to releasably couple to a second portion of the optical connector, wherein the coupler comprises a first portion to which light is incident from the optical connector, and a second portion in which the light passes through an inside of the coupler and is emitted, wherein the first portion is tilted with a predetermined angle with respect to the second portion.

Provided herein are imaging systems for a patient including an imaging probe and an imaging assembly. The imaging probe includes: an elongate shaft with a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion; a rotatable optical core with a proximal end and a distal end, and at least a portion of the rotatable optical core is positioned within the lumen of the elongate shaft; and an optical assembly positioned proximate the distal end of the rotatable optical core, the optical assembly configured to direct light to tissue to be imaged and collect reflected light from the tissue to be imaged. The imaging assembly is constructed and arranged to optically couple to the imaging probe. The imaging assembly is configured to emit light into the imaging probe and receive the reflected light collected by the optical assembly.

An image capturing apparatus includes: a columnar main body having proximal and distal ends, and having a predetermined length therebetween so as to enable insertion of at least the distal end into an oral cavity; at least one light source provided on the proximal or distal end side of the main body, or to the main body, configured to emit light having a predetermined frequency band; a diffuser plate provided on the proximal or distal end side of the main body, or to the main body, configured to diffuse the emitted light toward the oral cavity; and a camera provided on the proximal or the distal end side of the main body, or to the main body, configured to capture an object image based on reflected light which has been diffused by the diffuser plate and reflected from the oral cavity.

A medical system includes a processor. The processor is configured to calculate a presence probability of a lesion in a not-yet-observed region inside a hollow organ of a patient, the not-yet-observed region being specified on the basis of an image that has been captured by an imaging sensor of an endoscope inside the hollow organ, and spatial disposition information of a distal end of an insertion part of the endoscope.

The endoscope has an insertion portion, an imaging unit, and a member formed in a given dimension. The insertion portion has an apical portion, an actively curvable portion, and a treatment device channel. The actively curvable portion is located on the proximal side of the apical portion. The treatment device channel is positioned along the longitudinal axis of the insertion portion. The insertion portion is formed of resin. One or more radiopaque members, formed of knowns dimensions, are coated on a surface of the insertion portion or placed in, buried or covered laterally in the insertion portion. The X-ray transmittance of the radiopaque members is different from the X-ray transmittance of the resin forming the insertion portion.

A medical image processing device a reference image that is a medical image with which boundary line information related to a boundary line that is a boundary between an abnormal region and a normal region and landmark information related to a landmark that is a characteristic structure of the subject are associated and a captured image that is the medical image captured in real time, detects the landmark from the captured image, calculates a ratio of match between the landmark included in the reference image and the landmark included in the captured image, estimates a correspondence relationship between the reference image and the captured image on the basis of the ratio of match and information regarding the landmarks included in the reference image and the captured image, and generates a superimposition image in which the boundary line associated with the reference image is superimposed on the captured image on the basis of the correspondence relationship.

A light source device includes: a first light source configured to emit first light including a white wavelength band or one or more wavelength bands of at least red, green, and blue; a second light source configured to emit second light including a specific wavelength band included in the first light; a first detector configured to detect an amount of the light of the specific wavelength band in the first light; a first optical member configured to multiplex light of a wavelength band different from the specific wavelength band in the first light, and the second light; and a processor configured to control the first light source based on a detection result of the first detector.

An endoscope or the like that prevents crosstalk between multiple light-emitting parts is provided. An endoscope includes: an observation window that is disposed at a distal end of an insertion part; a plurality of first light-emitting parts that are disposed around the observation window; a second light-emitting part that is disposed between the first light-emitting parts and emits light at a bandwidth different from a bandwidth of light emitted by the first light-emitting parts; and a light-shielding body that is disposed between one of the first light-emitting parts and the second light-emitting part.