Patent classifications
C07C309/75
NON-CHROMATOGRAPHIC PURIFICATION OF MACROCYCLIC PEPTIDES BY A RESIN CATCH AND RELEASE
The disclosure is directed to the synthesis and improved methods for purifying macrocyclic peptides produced by solid phase peptide synthesis.
Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Rosacea
The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, rosacea.
Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Rosacea
The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, rosacea.
Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Skin Cancer
The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, skin cancer.
Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Skin Cancer
The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, skin cancer.
SULFONIC ACID ESTER COMPOUND AND USE THEREFOR
Provided is a sulfonic acid ester compound represented by formula (1).
##STR00001##
(In the formula, R.sup.1 and R.sup.2 each independently represent a hydrogen atom, or a straight-chain or branched monovalent aliphatic hydrocarbon group. R.sup.3 represents a straight-chain or branched monovalent aliphatic hydrocarbon group. The sum of the carbon numbers of R.sup.1, R.sup.2 and R.sup.3 is 6 or greater. A.sup.1 represents O or S. A.sup.2 represents an aromatic group having a valence of (n+1). A.sup.3 represents a hydrocarbon group which has a valence of m, and is unsubstituted or has a substituent that contains one or more aromatic rings. m represents an integer satisfying 2m4. n represents an integer satisfying 1n4.)
SULFONIC ACID ESTER COMPOUND AND USE THEREFOR
Provided is a sulfonic acid ester compound represented by formula (1).
##STR00001##
(In the formula, R.sup.1 and R.sup.2 each independently represent a hydrogen atom, or a straight-chain or branched monovalent aliphatic hydrocarbon group. R.sup.3 represents a straight-chain or branched monovalent aliphatic hydrocarbon group. The sum of the carbon numbers of R.sup.1, R.sup.2 and R.sup.3 is 6 or greater. A.sup.1 represents O or S. A.sup.2 represents an aromatic group having a valence of (n+1). A.sup.3 represents a hydrocarbon group which has a valence of m, and is unsubstituted or has a substituent that contains one or more aromatic rings. m represents an integer satisfying 2m4. n represents an integer satisfying 1n4.)
Photoacid generators and lithographic resists comprising the same
The present invention provides photoacid generators for use in chemically amplified resists and lithographic processes using the same.
Photoacid generators and lithographic resists comprising the same
The present invention provides photoacid generators for use in chemically amplified resists and lithographic processes using the same.
Non-chromatographic purification of macrocyclic peptides by a resin catch and release
The disclosure is directed to the synthesis and improved methods for purifying macrocyclic peptides produced by solid phase peptide synthesis. The synthesized peptide is capped with an alkyne-functionalized or azide-functionalized compound of formula (I): ##STR00001##
prior to cleavage of the peptide from the solid phase support.