An endoscopic imaging system for use in a light deficient environment includes an imaging device having a tube, one or more image sensors, and a lens assembly including at least one optical elements that corresponds to the one or more image sensors. The endoscopic system includes a display for a user to visualize a scene and an image signal processing controller. The endoscopic system includes a light engine having an illumination source generating one or more pulses of electromagnetic radiation and a lumen transmitting one or more pulses of electromagnetic radiation to a distal tip of an endoscope.

An irradiation module mechanically detachably attached to a light source module includes a first light source light entrance end which allows entry of first light source light from a first light source module, a first light guide member to guide the first light source light entered the first light source light entrance end, a second light source light entrance end which allows entry of second light source light from a second light source module, and a second light guide member to guide the second light source light entered the second light source light entrance end. The first light guide member and the second light guide member have optical specifications which correspond to optical characteristics of the light source light to be guided and in which the optical characteristics are different from each other.

An endoscope optical system unit according to the present invention, includes, an endoscope illuminating optical system which includes, a light-emitting section, and a first optical-path deflecting prism group which takes in illumination light emitted from the light-emitting section, and irradiates light to a subject upon deflecting an optical path, and the first optical-path deflecting prism group includes three prisms in order from an object side which are, a first prism, a second prism, and a third prism, and the first prism, the second prism, and the third prism are disposed to be mutually adjacent, and a direction of irradiation of the illumination light is let to be variable to a first direction by rotationally moving the first prism with respect to the second prism, and the direction of irradiation of the illumination light is let to be variable to a second direction which differs from the first direction, by rotationally moving the first prism and the second prism integrally, with respect to the third prism; and an endoscope objective optical system, wherein the endoscope objective optical system includes a second optical-path deflecting prism group, and a lens group, and the second optical-path deflecting prism group includes three prisms in order from the subject side, a fourth prism, a fifth prism, and a sixth prism, and the fourth prism, the fifth prism, and the sixth prism are disposed to be mutually adjacent, and a visual field direction is let to be variable to the first direction by rotationally moving the fourth prism with respect to the fifth prism, and the visual field direction is let to be variable to the second direction which differs from the first direction, by rotationally moving the fourth prism and the fifth prism integrally, with respect to the sixth prism, and the first optical-path deflecting prism group and the second optical-path deflecting prism group are disposed such that a third axis of rotation when the fourth prism rotates with respect to the fifth prism, and a first axis of rotation when the first prism of the endoscope illuminating optical system rotates with respect to the second prism, become coaxial, and the first optical-path deflecting prism group and the second optical-path deflecting prism group are disposed such that a fourth axis of rotation when the fourth prism and the fifth prism rotate integrally with respect to the sixth prism, and a second axis of rotation when the first prism and the second prism rotate integrally with respect to the third prism, become coaxial, and both the visual field direction of the endoscope objective optical system and the direction of irradiation of the illumination light of t

Image rotation in an endoscopic laser mapping imaging system is described. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a rotation sensor for detecting an angle of rotation of a lumen relative to a handpiece of an endoscope. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter is a laser mapping pattern.

A lighting device is disclosed with excitation light source(s) for emitting excitation light along an excitation light path; a wavelength conversion assembly including wavelength conversion element(s) for converting the excitation light into conversion light and emitting it into the same half-space from which the excitation light is radiated onto the surface of the element, and reflection element(s) for reflecting, in unconverted fashion, the excitation light intermittently radiated onto the reflection element from the source(s) along the portion of the excitation light path onto a reflection light path as reflection light; and a dichroic mirror for deflecting the excitation light coming from the source(s) onto the portion of the excitation light path on which the excitation light is radiated onto the wavelength conversion element(s) or the reflection element(s). The mirror is configured such that the conversion light is transmitted through the mirror and the reflection light is guided past the mirror.

Provided is a scanning endoscope apparatus capable of generating an image having an optimum SNR. The scanning endoscope apparatus includes: a light source; an optical fiber that guides light emitted from the light source; an actuator that deflects light emitted from the optical fiber and repeatedly scans the deflected light on the irradiation object; a light detector with a controllable multiplication factor, the light detector photoelectrically converting signal light obtained from the irradiation object irradiated with the light; and a controller, the controller controlling the multiplication factor so as to optimize a SNR based on electric signals obtained for a certain period, the signals having been photoelectrically converted by the optical detection unit.

Fluorescence imaging with reduced fixed pattern noise is disclosed. A method includes actuating an emitter to emit a plurality of pulses of electromagnetic radiation and sensing reflected electromagnetic radiation resulting from the plurality of pulses of electromagnetic radiation with a pixel array of an image sensor. The method includes reducing fixed pattern noise in an exposure frame by subtracting a reference frame from the exposure frame. The method is such that at least a portion of the plurality of pulses of electromagnetic radiation emitted by the emitter comprises electromagnetic radiation having a wavelength from about 795 nm to about 815 nm.

A color image sensor captures a reflected image of narrowband light having a wavelength range in which an extinction coefficient varies with a change in an oxygen saturation level of hemoglobin in blood. Thereby a first blue signal, a first green signal, and a first red signal are obtained. The color image sensor captures a reflected image of white light. Thereby a second blue signal, a second green signal, and a second red signal are obtained. Only an oxygen saturation level, out of two or more types of biological functional information including a blood volume and the oxygen saturation level, is obtained based on the first blue signal, the second green signal, and the second red signal. The oxygen saturation level is visualized to produce an oxygen saturation image.

First RGB image signals are inputted. A first B/G ratio and a first G/R ratio are calculated. The first B/G ratio and the first G/R ratio are converted into a second B/G ratio and a second G/R ratio, respectively, through a color information conversion process. Owing to the color information conversion process, a difference between first and second observation areas in a second signal ratio space formed by the second B/G ratio and the second G/R ratio is greater than a difference between the first and second observation areas in a first signal ratio space formed by the first B/G ratio and the first G/R ratio, and a difference between the first and third observation areas in the second signal ratio space is greater than a difference between the first and third observation areas in the first signal ratio space.

An optical endoluminal far-field microscopic imaging catheter comprises a light generating system, a first light delivery conduit for propagating light generated by the light generating system and a light distributor configured to redirect light propagated by the delivery conduit into a direction of an object to be imaged. A discriminator is configured for capturing light reflected from the object incident on a window of the discriminator from a particular direction and transmitting only the light captured from the particular direction to a second light delivery conduit. A drive mechanism is configured to sweep the window through a plurality of directions in a predictable pattern for matching each light capture event in the window with a direction of the window during the event. An analyzer matches the direction of the window with an associated light capture event and generate a visible image based on a mosaic of the captured light.