Patent classifications
C07C311/13
TEAD INHIBITORS AND USES THEREOF
The present disclosure provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING
Disclosed herein are FABP4 and FABP5 inhibitor compounds and their use in pharmaceutical compositions for treating diseases relating to fatty acid metabolism, including cancer. Also disclosed herein are methods for preparing the disclosed compounds.
FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING
Disclosed herein are FABP4 and FABP5 inhibitor compounds and their use in pharmaceutical compositions for treating diseases relating to fatty acid metabolism, including cancer. Also disclosed herein are methods for preparing the disclosed compounds.
Inhibitors of alpha 2 beta 1 integrin and methods of use thereof
Disclosed herein, inter alia, are inhibitors of alpha 2 beta 1 integrin and methods of using the same.
NAMPT MODULATORS
Provided are compounds of Formula (II) or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, and p are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula (II), or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula (II), or a pharmaceutically acceptable salt thereof.
##STR00001##
SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES
Provided is a compound of Formula (I):
##STR00001## wherein the variable groups are defined herein.
SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES
Provided is a compound of Formula (I):
##STR00001## wherein the variable groups are defined herein.
2,2' -DIAMINO BIARYLS WITH TWO SECONDARY AMINES AND PRODUCTION THEREOF BY ELECTROCHEMICAL COUPLING
Novel 2,2′-diamino biaryls of formula (I), (II) and (III), wherein R1-R10, R1′-R10′, X1-X3 and X1-X3′ are defined in claim 1. The invention also relates to an electrochemical method for the production thereof.
2,2' -DIAMINO BIARYLS WITH TWO SECONDARY AMINES AND PRODUCTION THEREOF BY ELECTROCHEMICAL COUPLING
Novel 2,2′-diamino biaryls of formula (I), (II) and (III), wherein R1-R10, R1′-R10′, X1-X3 and X1-X3′ are defined in claim 1. The invention also relates to an electrochemical method for the production thereof.
High affinity beta lactamase inhibitors
Inhibitors of beta lactamases and their use in treating bacterial infections are disclosed.