Patent classifications
C07C311/13
High affinity beta lactamase inhibitors
Inhibitors of beta lactamases and their use in treating bacterial infections are disclosed.
SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
PROCESS FOR THE PREPARATION OF RILPIVIRINE
The present invention relates to a new process of preparation of Rilpivirine, or a pharmaceutically acceptable salt thereof. Another aspect of the invention concerns compounds of formulae II and III: and their salts thereof, and their use for the preparation of Rilpivirine or a suitable salt thereof.
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PROCESS FOR THE PREPARATION OF RILPIVIRINE
The present invention relates to a new process of preparation of Rilpivirine, or a pharmaceutically acceptable salt thereof. Another aspect of the invention concerns compounds of formulae II and III: and their salts thereof, and their use for the preparation of Rilpivirine or a suitable salt thereof.
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Modulators of Sestrin-GATOR2 interaction and uses thereof
The present invention provides compounds, compositions thereof, and methods of using the same.
Modulators of Sestrin-GATOR2 interaction and uses thereof
The present invention provides compounds, compositions thereof, and methods of using the same.
Processes and intermediates for preparing MCL1 inhibitors
The present disclosure provides methods for preparing MCL1 inhibitors or a salt thereof and related key intermediates.
Processes and intermediates for preparing MCL1 inhibitors
The present disclosure provides methods for preparing MCL1 inhibitors or a salt thereof and related key intermediates.
Processes and intermediates for preparing MCL1 inhibitors
The present disclosure provides methods for preparing MCL1 inhibitors or a salt thereof and related key intermediates.