Patent classifications
C07C311/13
MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF
The present invention provides compounds, compositions thereof, and methods of using the same.
PHENYL CYCLOHEXANONE DERIVATIVES AND METHODS OF MAKING AND USING THEM
Phenyl cyclohexanone based active agents, pharmaceutical preparations containing such active agents, methods of modifying cellular activity by contacting cells with such active agents, and methods of treating various conditions by administering such active agents to a patient are described.
PHENYL CYCLOHEXANONE DERIVATIVES AND METHODS OF MAKING AND USING THEM
Phenyl cyclohexanone based active agents, pharmaceutical preparations containing such active agents, methods of modifying cellular activity by contacting cells with such active agents, and methods of treating various conditions by administering such active agents to a patient are described.
Aryl alkynamide derivatives
[Problem] A compound which is useful as a STING inhibitor is provided. [Means for Solution] The present inventors have found aryl alkynamide derivatives having an inhibitory action on STING. The aryl alkynamide derivatives of the present invention have an inhibitory action on STING and can be used as an agent for treating an autoimmune disease, a neurodegenerative disease, a type I interferonopathy and/or other STING-mediated disease.
Aryl alkynamide derivatives
[Problem] A compound which is useful as a STING inhibitor is provided. [Means for Solution] The present inventors have found aryl alkynamide derivatives having an inhibitory action on STING. The aryl alkynamide derivatives of the present invention have an inhibitory action on STING and can be used as an agent for treating an autoimmune disease, a neurodegenerative disease, a type I interferonopathy and/or other STING-mediated disease.
Compounds and methods for inducing chondrogenesis
Described herein are compounds and compositions for the amelioration of arthritis or joint injuries by inducing mesenchymal stem cells into chondrocytes.
Compounds and methods for inducing chondrogenesis
Described herein are compounds and compositions for the amelioration of arthritis or joint injuries by inducing mesenchymal stem cells into chondrocytes.
SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES
Provided is a compound of Formula (I):
##STR00001## wherein the variable groups are defined herein.
PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS
The present disclosure provides methods for preparing MCL1 inhibitors or a salt thereof and related key intermediates.
PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS
The present disclosure provides methods for preparing MCL1 inhibitors or a salt thereof and related key intermediates.