C07C311/38

Cyclic vinylogous amides as bromodomain inhibitors

Cyclic vinylogous amides of Formula I are disclosed ##STR00001## The compounds are useful for treating diseases that arise from inappropriate activity of proteins containing an acetyl-lysine. The compositions comprise a genus of cyclic vinylogous amides that are inhibitors of bromodomain.

Cyclic vinylogous amides as bromodomain inhibitors

Cyclic vinylogous amides of Formula I are disclosed ##STR00001## The compounds are useful for treating diseases that arise from inappropriate activity of proteins containing an acetyl-lysine. The compositions comprise a genus of cyclic vinylogous amides that are inhibitors of bromodomain.