An overtube that includes a body, a first duct for housing a first insertion tube of a first endoscope, where the first duct is arranged longitudinally within the body and opens at the distal end, a second duct for housing a second insertion tube of a second endoscope, where the second duct is arranged longitudinally within the body and opens at the distal end, a first orifice for introducing the first insertion tube into the first duct, a second orifice for introducing the second insertion tube into the second duct, a third orifice for introducing a lubricant into the first duct and into the second duct, and where the first duct and the second duct communicate with each other via a communication passage, and the passage opens at the third orifice.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

A holding mechanism includes a fixed holding portion and a rotary holding portion. The rotary holding portion switches the holding state of the holding mechanism by rotation to either a first state in which the rotary holding portion holds, together with the fixed holding portion, a guide member at the operation portion, or the second state in which the rotary holding portion fixes, together with the fixed holding portion, the guide member.

An apparatus for treating obesity of a patient having a stomach with a food cavity. The apparatus comprising a volume filling device adapted to be at least substantially invaginated by a stomach wall portion of the patient with the outer surface of the volume filling device resting against the stomach wall, such that the volume of the food cavity is reduced in size by a volume substantially exceeding the volume of the volume filling device. The apparatus further comprises at least one adjustable stretching device adapted to be at least substantially invaginated by a stomach wall portion of the patient with the outer surface of the stretching device resting against the stomach wall and adapted to stretch a portion of stomach wall, and a fluid connection device interconnecting the volume filling device and the stretching device.

An adaptor may include a shell and a plunger positioned at a first end of the shell and moveable between an undepressed state and a depressed state. The adaptor may further include a ramp extending from a second end of the shell and a carrier coupled to the ramp. In the undepressed state, the carrier may be located at a first position along the ramp, and wherein, in the depressed state, the carrier may be located at a second position along the ramp, wherein the second position may be closer to the second end of the shell than the first position.

Disclosed herein are intestine pleating methods and devices for use with gastrointestinal endoscopes. Devices include balloon access device, attachable structure(s), and an elongate overtube. Attachable structures may be used to pleat intestinal wall and to advance the endoscope past difficult to navigate areas. Balloon access device may be used to improve visualization of intestinal wall and to pleat intestinal wall. These systems may be used during airless endoscopic procedures that do not require insufflation of the intestinal cavity. The systems may be used during airless intubation procedures. To pleat the intestine, the practitioner inflates balloon to a fully or nearly fully inflated state when a difficult area is encountered. Inflation of the balloon to fully or nearly fully inflated state ensures contact with intestinal wall. Practitioner pulls back on the endoscope shaft to drag intestinal wall back toward the proximal opening of intestinal cavity. Pleating facilitates forward advancement of endoscope.

A procedure for reducing the effective volume of the stomach of a patient involves a balloon module which is introduced into the stomach by either a gastroscope or through a catheter inserted through the stomach wall. The balloon module has a pair of positioning strings and a balloon with an integral protruding tube. After introduction into the stomach, the balloon is inflated and secured in position by the positioning strings. The position of the balloon in the stomach may be monitored by a contrast medium introduced into the balloon.

A surgical computing system may receive usage data associated with movement of a surgical instrument and user inputs to the surgical instrument. The surgical computing system may receive motion and biomarker sensor data from sensing systems applied to the operator of the surgical instrument. The surgical computing system may determine, based on at least one of the usage data and/or the sensor data, an evaluation of the actions of the operator of the surgical instrument. The surgical computing system may determine, based on the evaluation, to provide feedback. The feedback may comprise instructions for the surgical instrument to provide haptic feedback and/or to modify its configuration. The feedback may comprise instructions for a display unit to present notifications instructing the healthcare professional. The surgical computing system may communicate instructions for providing the feedback to the surgical instrument and/or the display unit.

A system can include an elongated member that includes a proximal portion and a distal portion that includes an agitator. The elongated member can extend through a working channel of an endoscope placed within a patient such that the agitator extends past a distal end of the endoscope into a target region within the patient. The agitator can include a plurality of disruption elements that can be in a low-profile state when within the working channel of the endoscope and can transition to an expanded state when advanced past the distal end of the endoscope. The plurality of disruption elements can define an empty cage configuration when in the expanded state. The system can include a driver coupled to the proximal portion of the elongated member. The driver can rotate the elongated member about a longitudinal axis of the elongated member.

The stomach tube is a transparent conduit in the form of a plastic tube which is equipped with an optical fibre with illuminating external surface. Its internal end is placed in the section of the stomach tube for insertion in the patient's stomach. An external end for connection with a light source is provided outside the stomach tube in the section of the stomach tube remaining outside the patient's body. The conduit of the stomach tube in its interior includes a first channel which is a transport channel, and a second channel in which the optical fibre is located. The stomach tube is intended for use in bariatric surgery procedures, and in particular in the sleeve gastrectomy procedure.