One embodiment is directed to a system comprising a head-mounted member removably coupleable to the user's head; one or more electromagnetic radiation emitters coupled to the head-mounted member and configured to emit light with at least two different wavelengths toward at least one of the eyes of the user; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering at least one blood vessel of the eye; and a controller operatively coupled to the one or more electromagnetic radiation emitters and detectors and configured to cause the one or more electromagnetic radiation emitters to emit pulses of light while also causing the one or more electromagnetic radiation detectors to detect levels of light absorption related to the emitted pulses of light, and to produce an output that is proportional to an oxygen saturation level in the blood vessel.

One embodiment is directed to a system comprising a head-mounted member removably coupleable to the user's head; one or more electromagnetic radiation emitters coupled to the head-mounted member and configured to emit light with at least two different wavelengths toward at least one of the eyes of the user; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering at least one blood vessel of the eye; and a controller operatively coupled to the one or more electromagnetic radiation emitters and detectors and configured to cause the one or more electromagnetic radiation emitters to emit pulses of light while also causing the one or more electromagnetic radiation detectors to detect levels of light absorption related to the emitted pulses of light, and to produce an output that is proportional to an oxygen saturation level in the blood vessel.

A method and system for determining visual related physical conditions of a user of a display device, determined from the user's responses to a selection of visual-tasks. A dataset is provided for correlating the user's responses with the corresponding scores, so that by measuring the degree of correlation between the user's scores and a predetermined combination of the corresponding scores, the user's visual physical condition can be determined. A system is also provided, including a user device as well as a remote server for providing visual acuity and related testing to detect certain vision deficiencies and visual related physical conditions. In addition, a user device application is provided.

A computerized method for administering a low luminance dysfunction test, comprising the steps of: (a) displaying a first character in a color at a first acuity level against a display having a luminance level; (b) receiving a first input signal from a patient via an input device, where the input signal is indicative of whether the patient recognizes the first character displayed in the first acuity level; (c) displaying a second character in the color at a second acuity level against the display having the luminance level; (d) receiving a second input signal from the patient via the input device, where the input signal is indicative of whether the patient recognizes the second character displayed at the second acuity level; and, (e) calculating a score based on the first and second input signals.

Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

A computer, a high resolution monitor and a patient interface is utilized to implement a visual contrast sensitivity function measurement test. More specifically, a computerized video system is configured to implement a tilted-grating forced choice contrast sensitivity function test. The invention utilizes known measurement methods for the visual contrast sensitivity function and automates their use by computerizing the system and couples it with a patient-interactive user interface in order to produce an accurate quantitative result.

Disclosed herein is a rodent and human behavioral test for evaluating visual dysfunctions associated with the retinal changes in Alzheimer disease progression. In one example, the inventors developed a maze that tests rodent's ability to identify (1) specific contrasts, (2) specific colors, (3) certain items in the visual field, and (4) other ‘non-typical’ peripheral and night vision functions associated with AD. For instance, the inventors developed a maze the tests the rodents ability to avoid certain colors or contrasts gradients. The maze may include certain rooms with specific visual markers (e.g., colors, contrasts, objects or other visual features) that also contain shock plates.

A display unit (16) outputs a stimulating image to an external display device (20). The stimulating image is obtained by synthesizing a luminance map in which luminance of each pixel is set in such a manner that a change in the luminance along a first axis follows a given spatial frequency, and a contrast map in which contrast of each pixel is set in such a manner that the contrast gradually decreases from one end to another end along a second axis and that an equal contrast line forms a given waveform. A response data generation unit (22) acquires a contrast value corresponding to each of the coordinates acquired by a user input receiving unit (21). A sensitivity calculation unit (23) calculates contrast sensitivity. A result output unit (25) outputs contrast sensitivity while adding reliability of the contrast sensitivity calculated by a reliability calculation unit (24) thereto.

A system for replicating a standardized visual acuity test, such as the 20′ Snellen test may comprise a binocular viewer attached to a smartphone. A binocular viewer may comprise a housing comprising a pair tube covers having voids allowing for viewing through a pair of lens tubes with each lens tube in visual communication with a second lens a first lens an aperture and a front cover. The optical systems use an artful combination of front and back lens surfaces, demagnification and other systems to faithfully replicate the sight lines perceived by a user of a traditional 20′ test. The system also allows for the incorporation of other tests conducted with both eyes including Color Sensitivity and Contrast, furthermore by placing a deformable, tunable lens between the second lens and the eye the device serves as an ophthalmic refractometer, allowing a Spherical Equivalent refraction estimate for each eye.