The present invention is directed to styryl quinolinium compounds, a process for their synthesis and their use for selective nucleoli staining in cells, preferably in living cells and for imaging rRNA.

The present invention is directed to styryl quinolinium compounds, a process for their synthesis and their use for selective nucleoli staining in cells, preferably in living cells and for imaging rRNA.

The invention relates to compounds of the general formulae (I)-(IV), which are characterized by substituents B comprising one or more sulfonic acid groups and their use as marker groups for the detection of analytes.

The invention relates to compounds of the general formulae (I)-(IV), which are characterized by substituents B comprising one or more sulfonic acid groups and their use as marker groups for the detection of analytes.

Disclosed herein are symmetrical and unsymmetrical carbocyanine dyes. Irradiation of the dyes generates reactive species which contribute to DNA damage. The dyes are useful for the treatment of various cancers and cell growth disorders.

Described herein are compounds that inhibits the membrane proximal external region (MPER) of a viral envelope (Env), as well as and compositions thereof. Further provided herein are methods for treating or preventing a viral infection comprises administering to a subject in need thereof an agent or compound that inhibits the MPER of a viral Env. In certain embodiments, the viral infection is an HIV infection.

A method of reducing color in an alkanolamine is described. The method includes contacting the alkanolamine with a color-reducing amount of a borane complex effective to provide a color-reduced alkanolamine composition having a Platinum-Cobalt Color Value, according to Test Method ASTM D1209, of less than 50.

A process for removing heavy polycyclic aromatic contaminants from a hydrocarbon stream using a quinolinium ionic liquid is described. The process includes contacting the hydrocarbon stream comprising the contaminant with a hydrocarbon-immiscible quinolinium ionic liquid to produce a mixture comprising the hydrocarbon and a hydrocarbon-immiscible quinolinium ionic liquid comprising at least a portion of the removed contaminant; and separating the mixture to produce a hydrocarbon effluent having a reduced level of the contaminant and a hydrocarbon-immiscible quinolinium ionic liquid effluent comprising the hydrocarbon-immiscible quinolinium ionic liquid comprising at least the portion of the removed contaminant.

A process for removing heavy polycyclic aromatic contaminants from a hydrocarbon stream using a quinolinium ionic liquid is described. The process includes contacting the hydrocarbon stream comprising the contaminant with a hydrocarbon-immiscible quinolinium ionic liquid to produce a mixture comprising the hydrocarbon and a hydrocarbon-immiscible quinolinium ionic liquid comprising at least a portion of the removed contaminant; and separating the mixture to produce a hydrocarbon effluent having a reduced level of the contaminant and a hydrocarbon-immiscible quinolinium ionic liquid effluent comprising the hydrocarbon-immiscible quinolinium ionic liquid comprising at least the portion of the removed contaminant.

The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof:

##STR00001##

The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, cough, itch, and neurogenic inflammation.