A diagnosis method includes: (a) checking tear film break-up time point and location by photographing cornea of the subject's eye and checking in time series at least one or more times of the tear film break-up time point; (b) checking corneal surface temperature by measuring the surface temperature of the cornea of the subject to be evaluated using a thermal imaging camera performed simultaneously with the photographing of the tear film of the eye; (c) mapping the tear film break-up time point and the change in the surface temperature of the cornea based on time; and (d) diagnosing type of dry eye syndrome based on any one of the tear film break-up time point and a location of surface temperature change time point of the corneal corresponding thereto, in mapping result in step (c).

A contact lens includes a contact lens body and a glucose detection sheet disposed on the contact lens body. The glucose detection sheet includes a glucose recognition layer, a photonic crystal array is provided in the glucose recognition layer, and the glucose recognition layer is configured to recognize glucose.

In an ophthalmologic apparatus, including: an objective lens that faces a subject's eye; an illumination optical system that irradiates a cornea of the subject's eye with illumination light through the objective lens; and a corneal measurement optical system including an interference image capturing camera that takes an image of a corneal reflection light, which is a reflection of the illumination light reflected from the cornea, through the objective lens, a numerical aperture G of the illumination optical system is larger than a numerical aperture g of the corneal measurement optical system.

The present invention relates to a contact lens for diagnosis and treatment of dry eye syndrome. The contact lens, according to the present invention, may diagnose dry eye syndrome by means of a change in an electric current occurring as a result of a field effect when a dry eye syndrome biomarker binds to a probe, and when dry eye syndrome is diagnosed, generates an electric current so that a gold film blocking a drug reservoir melts by the electric current, thereby enabling the release of a drug to be controlled.

An evaluation device for tear secretion uses an air nozzle and a thermal camera device to cause minor irritations to the eyes and record the temperature changes of the eyes to evaluate the quantity of the tear secretion and to determine whether the subject is able to perform reflex tearing normally or not.

A method for collecting biometric measurement data of an eye on the basis of different measurement modalities, allowing for physiologically correct, representative, and robust biometric measurement data. In the method, the measurement data for individual measurement variables and the dynamic behavior of the eye are recorded continuously at the highest possible repetition rate over the measurement time. The individual phases of the dynamics of the eye which define the limits of the phase for stable vision are analyzed on the basis of the measurement values, and only the measurement data for the individual measurement variables are output which have been detected during the phase for stable vision. Although the proposed method is provided for collecting biometric measurement data in preparation for a cataract operation, the method can also be applied to other areas of ophthalmology to generate error-free measurement data or recordings of the eye.

Provided are a method, a computer program and a device for noninvasively evaluating a state of a tear fluid and a tear fluid amount of a tear meniscus. Included are a binarization step of binarizing a tear meniscus image, obtained by capturing at least a part of a tear meniscus of a subject, using a predetermined threshold value; an extraction step of extracting a high luminance region indicating a tear meniscus part from the binarized image; and an evaluation step of evaluating a tear fluid state on the basis of the high luminance region.

Systems and methods for monitoring eyedrop usage are disclosed. Example embodiments include a system to monitor eyedrop usage. The system may include a detection and activation circuit couplable to a wireless biosensor and an eyedrop dispenser. The detection and activation circuit may include a pressure transducer that transmits a signal upon detecting a force at, or above, a threshold value. The system may also include a wireless biosensor insertable into a region of an eyelid. The wireless biosensor may include a sensor to detect the physical change and the chemical change of tears as a result of eyedrop usage. The wireless biosensor may also include a transceiver to receive the signal that activates the sensor for an activation time.

An ophthalmologic apparatus includes: an objective lens that faces a subject's eye; a first illumination optical system that irradiates a cornea of the subject's eye with illumination light; and a corneal measurement optical system having an imaging element that takes an image of a corneal reflection light, which is a reflection of the illumination light, through the objective lens, and outputs an imaging signal. The corneal measurement optical system includes a first mirror arranged near the objective lens and a second mirror arranged near the imaging element. The first and second mirrors and are configured such that the corneal reflection light that enters and is reflected from the first mirror, and then enters and is reflected from the second mirror exits toward an incident side from which the corneal reflection light enters a reflection surface of the first mirror.

An apparatus and a method for measuring physiological parameters of an eye. The apparatus includes a transmitter for transmitting a first set of electromagnetic waves of a first set of frequencies towards the eye, a receiver for receiving reflected electromagnetic waves corresponding to the transmitted first set of electromagnetic waves of the first set of frequencies, a comparator configured to compare the transmitted first set of electromagnetic waves with the received reflected electromagnetic waves for determining an amplitude response and a phase response for each of the electromagnetic waves of the first set of frequencies, and a calculation unit configured to fit the determined amplitude response and phase response to a physiological model of the eye to determine the physiological parameters of the eye.