A terminally modified polycarbonate resin that has ultraviolet absorbing capability is provided. More specifically, the terminally modified polycarbonate resin has a structure represented by general formula (A) and a constituent unit that is derived from a dihydric phenol. (In general formula (A), R.sub.1 represents a hydrogen atom or an alkyl group having 1-6 carbon atoms; R.sub.2 represents an alkylene group having 1-6 carbon atoms; R.sub.3 represents a hydrogen atom or a methyl group; R.sub.4 represents a hydrogen atom or a halogen atom; and * represents the bonding position to the main chain of the polycarbonate resin.) ##STR00001##

Substituted aromatic sulfonamides of formula (I) pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease.

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The present invention relates to an eyeglass lens comprising a substrate made of an optical material comprising a polymer matrix and at least one 2-(2-hydroxy-5-R.sup.1-phenyl)benzotriazole, in which R.sup.1 is a resonant group, the optical transmittance through a 2 mm thick layer of said optical material being lower than 1% for each light wavelength ranging from 280 to 405 nm. This eyeglass lens protects from phototoxic blue light and UV light.

The present invention relates to an eyeglass lens comprising a substrate made of an optical material comprising a polymer matrix and at least one 2-(2-hydroxy-5-R.sup.1-phenyl)benzotriazole, in which R.sup.1 is a resonant group, the optical transmittance through a 2 mm thick layer of said optical material being lower than 1% for each light wavelength ranging from 280 to 405 nm. This eyeglass lens protects from phototoxic blue light and UV light.

Provided are compounds of Formula (I):

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and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.

Provided are compounds of Formula (I):

##STR00001##

and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.

Optical material comprising a polymer matrix and at least one benzotriazole compound having at least one ester group, wherein said at least one benzotriazole is a chlorobenzotriazole compound that does not comprise any polymerizable group selected from allylic, acrylic and methacrylic moieties, or the optical transmittance through a 2 mm thick layer of said optical material is lower than 1% for each light wavelength ranging from 280 to 400 nm, and higher than 65% for light having a wavelength of 430 nm. This optical material can be used to protect from phototoxic blue light and UV light.

Optical material comprising a polymer matrix and at least one benzotriazole compound having at least one ester group, wherein said at least one benzotriazole is a chlorobenzotriazole compound that does not comprise any polymerizable group selected from allylic, acrylic and methacrylic moieties, or the optical transmittance through a 2 mm thick layer of said optical material is lower than 1% for each light wavelength ranging from 280 to 400 nm, and higher than 65% for light having a wavelength of 430 nm. This optical material can be used to protect from phototoxic blue light and UV light.

Described are high energy light blocking compounds and ophthalmic devices containing the compounds. In particular, described are hydroxybiphenyl benzotriazole structures with polymerizable functionality that block high energy light and are visibly transparent. The hydroxybiphenyl benzotriazole structures can be incorporated into ophthalmic devices, such as hydrogel contact lenses, to protect eyes from high energy light radiation.

Described are high energy light blocking compounds and ophthalmic devices containing the compounds. In particular, described are hydroxybiphenyl benzotriazole structures with polymerizable functionality that block high energy light and are visibly transparent. The hydroxybiphenyl benzotriazole structures can be incorporated into ophthalmic devices, such as hydrogel contact lenses, to protect eyes from high energy light radiation.