Patent classifications
C07D279/36
PHOTOSENSITIZER AND DERIVATIVES AND APPLICATION THEREOF
A photosensitizer and derivative, application thereof. The photosensitizer has the structure of general formula I, wherein X is S or Se, Y is organic or inorganic ion, R.sub.1 and R.sub.2 are independently selected from H, alkyl, alkoxy, alkyl amido, alkyl azide and the like; R.sub.3 is selected from H, alkyl, alkoxy, amino sulfonyl, hydroxyl, carboxyl and the like, and L.sub.1 is a linker selected from (CH.sub.2).sub.n1 or (CH.sub.2CH.sub.2O).sub.n2. The derivatives are molecular medicines with drug molecules of anticancer and chemotherapy or tumor targeting function connected to the said photosensitizer. The photosensitizer has excellent near infrared characteristics and low dark toxicity and is used in the field of photodynamic tumor therapy. The introduction of benzophenothiazine or benzophenoselenazine into derivatives with tumor-targeting function could improve the specific uptake of photosensitizer in tumor tissues. Moreover, clinical anticancer drugs can be introduced into the structure of benzophenothiazine or benzophenoselenazine to achieve the purpose of combining therapy of photodynamic therapy and chemotherapy.
##STR00001##
SMALL MOLECULE PROTEASOME ACTIVATORS AND USES THEREOF
The disclosure is directed to compounds of the formula (I) and (II) and uses of such compounds to treat, among other conditions, neurodegenerative diseases and cancers.
DIARYLAMINE-BASED COMPOUND, ANTI-AGING AGENT, AND POLYMER COMPOSITION
The present invention provides a diarylamine-based compound represented by General Formula (1):
##STR00001##
(where A.sup.1 and A.sup.2 each independently represent a C.sub.6 to C.sub.18 arylene group which may have a substituent, and A.sup.3 and A.sup.4 each independently represent an organic group having a cyclic imide structure which may have a substituent).
Materials for electronic devices
The present application relates to a compound of a formula (I) which comprises a benzene group that is substituted with a group selected from carbazole derivatives and bridged amines and with an electron attracting group, wherein the two groups are located in the ortho-position in relation to one another. The present application further relates to the use of the compound of the formula (I) in an electronic device, and to a method of producing the compound of the formula (I).
Materials for electronic devices
The present application relates to a compound of a formula (I) which comprises a benzene group that is substituted with a group selected from carbazole derivatives and bridged amines and with an electron attracting group, wherein the two groups are located in the ortho-position in relation to one another. The present application further relates to the use of the compound of the formula (I) in an electronic device, and to a method of producing the compound of the formula (I).
MATERIALS FOR ELECTRONIC DEVICES
The present invention relates to compounds according to formula (I), which are suitable for use in electronic devices, preferably organic electroluminescent devices.
MATERIALS FOR ELECTRONIC DEVICES
The present invention relates to compounds according to formula (I), which are suitable for use in electronic devices, preferably organic electroluminescent devices.
Substituted dibenzo[b, f]azepines as proteasome activators
The disclosure is directed to substituted dibenzo[b,f]azepines of the formula (II): ##STR00001## wherein the variables n, X.sup.3, R.sup.1, R.sup.2, R.sup.4, and R.sup.5 are defined herein, and uses of such compounds to treat conditions including neurodegenerative diseases and cancers.
ORGANIC ELECTROLUMINESCENT COMPONENT
The present invention relates to an OLED, comprising an anode, a cathode and one or more organic layers, and at least one of the organic layers comprising a material having the following chemical formula I or II. Since the compound having the formula (I) in the present invention has electron-withdrawing groups and electron-donating groups with high stability, stable chemical bonds exist between them, without strong conjugation. With these characteristics, the compound having the formula (I) has higher fluorescence quantum efficiency and excellent charge transport ability, and its emission spectra are closer to the international standard of dark blue, to facilitate to the realization of full-color displays with higher color purity.
##STR00001##
Materials for organic electroluminescent devices
The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds.