The present invention relates to epoxy-tigliane compounds and their use in promoting wound healing. In particular embodiments, the epoxy-tigliane compounds are epoxy-tigliaen-3-one compounds. Methods of inducing or promoting wound healing as well as methods of reducing scarring and improving cosmetic outcomes upon healing of a wound are described. Compounds and compositions for use in wound healing are also described.

The disclosure provides fumagillol type compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of using, e.g. in the treatment of obesity are provided.

The disclosure provides fumagillol type compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of using, e.g. in the treatment of obesity are provided.

The invention provides oxaspiro[2.5]octane derivatives and analogs, methods for preparation thereof, intermediates thereto, pharmaceutical compositions, and uses thereof in the treatment of various disorders and conditions, such as overweight and obesity.

The invention provides oxaspiro[2.5]octane derivatives and analogs, methods for preparation thereof, intermediates thereto, pharmaceutical compositions, and uses thereof in the treatment of various disorders and conditions, such as overweight and obesity.

A nematic liquid crystal composition having negative dielectric anisotropy (), and a liquid crystal device element including the liquid crystal composition. The liquid crystal composition has sufficiently low viscosity (), sufficiently low rotational viscosity (1), a large elastic constant (K.sub.33), and a negative dielectric anisotropy () whose absolute value is large, without reducing the refractive index anisotropy (n) or the nematic-isotropic liquid phase transition temperature (T.sub.ni). A VA-mode liquid crystal display element including the liquid crystal composition, the liquid crystal display element having no or minimal display defects and having excellent display quality and a fast response. The liquid crystal display element including the liquid crystal composition is useful for an active matrix-addressed liquid crystal display element and used for, for example, a VA- or PSVA-mode liquid crystal display element.

A nematic liquid crystal composition having negative dielectric anisotropy (), and a liquid crystal device element including the liquid crystal composition. The liquid crystal composition has sufficiently low viscosity (), sufficiently low rotational viscosity (1), a large elastic constant (K.sub.33), and a negative dielectric anisotropy () whose absolute value is large, without reducing the refractive index anisotropy (n) or the nematic-isotropic liquid phase transition temperature (T.sub.ni). A VA-mode liquid crystal display element including the liquid crystal composition, the liquid crystal display element having no or minimal display defects and having excellent display quality and a fast response. The liquid crystal display element including the liquid crystal composition is useful for an active matrix-addressed liquid crystal display element and used for, for example, a VA- or PSVA-mode liquid crystal display element.

The present invention relates to the well drilling field in petroleum industry, in particular to a nano-hybrid lubricant and method thereof, and oil-based drilling fluid. The lubricant comprises: graphite oxide and a biquaternary ammonium salt compound of which the cation part is represented by formula (1). The present invention also provides a method for preparation of the lubricant and an oil-based drilling fluid containing the lubricant. The lubricant provided in the present invention can be comprehended as a nano-hybrid material. Thus, oil-based drilling fluids that contain the lubricant provided in the present invention have lower lubrication coefficient and excellent lubricating property without or with little negative impact on rheological property of the oil fluid, and the lubricant provided in the present invention has excellent thermostability thus suitable for use in operation at a high temperature. ##STR00001##

The present invention relates to the well drilling field in petroleum industry, in particular to a nano-hybrid lubricant and method thereof, and oil-based drilling fluid. The lubricant comprises: graphite oxide and a biquaternary ammonium salt compound of which the cation part is represented by formula (1). The present invention also provides a method for preparation of the lubricant and an oil-based drilling fluid containing the lubricant. The lubricant provided in the present invention can be comprehended as a nano-hybrid material. Thus, oil-based drilling fluids that contain the lubricant provided in the present invention have lower lubrication coefficient and excellent lubricating property without or with little negative impact on rheological property of the oil fluid, and the lubricant provided in the present invention has excellent thermostability thus suitable for use in operation at a high temperature. ##STR00001##

A cover window according to an example embodiment of the present invention includes: a base film; and a coating layer positioned on the base film, in which the coating layer is formed through application of a coating solution. The coating solution includes a compound represented by the following Chemical Formula 1. ##STR00001## In Chemical Formula 1, R is CH.sub.3, R is an epoxy group, X, Y, and Z are each independently Si, and Y is 85% to 90% based on a total amount of X, Y and Z.