An ophthalmic image processing apparatus includes a processor. The processor acquires a first image as a color fundus image, and corrects a pixel value of at least any color component in the first image, based on color gamut information for specifying a predetermined color gamut to be applied to a color fundus image, to generate a color gamut-corrected image.

An ophthalmic image processing apparatus includes a processor. The processor acquires a first image as a color fundus image, and corrects a pixel value of at least any color component in the first image, based on color gamut information for specifying a predetermined color gamut to be applied to a color fundus image, to generate a color gamut-corrected image.

Retinal diseases, such as age-related macular degeneration (AMD), are the leading cause of blindness in the elderly population. Since no known cures are currently present, it is crucial to diagnose the condition in its early stages so that disease progression is monitored. Systems and methods for detecting and mapping the mechanical elasticity of retinal layers in the posterior eye are disclosed herein. A system including confocal shear wave acoustic radiation force optical coherence elastography (SW-ARF-OCE) is provided, wherein an ultrasound transducer and an optical scan head are co-aligned to facilitate in-vivo study of the retina. In addition, an automatic segmentation algorithm is used to isolate tissue layers and analyze the shear wave propagation within the retinal tissue to estimate mechanical stress on the retina and detect early stages of retinal diseases based on the estimated mechanical stress.

An ophthalmologic apparatus, includes: a first concave mirror and a second concave mirror having a concave surface-shaped first reflective surface and a concave surface-shaped second reflective surface; an SLO optical system configured to project light from an SLO light source onto a subject's eye via the first concave mirror and the second concave mirror, and to detect returning light from the subject's eye; a first optical scanner configured to deflect the light from the SLO light source to guide the light to the first reflective surface; a second optical scanner configured to deflect light reflected by the first reflective surface to guide the light to the second reflective surface; an OCT optical system including a third optical scanner, and configured to split light from an OCT light source into measurement light and reference light, to project the measurement light deflected by the third optical scanner onto the subject's eye, and to detect interference light between returning light of the measurement light from the subject's eye and the reference light; an optical path coupling member disposed between the first optical scanner and the first concave mirror, and combining an optical path of the SLO optical system and an optical path of the OCT optical system; and a correction unit configured to correct detection result of the interference light detected by the OCT optical system or an image formed based on the detection result.

An ophthalmologic apparatus includes an optical scanner, an interference optical system, an intraocular distance calculator, an image correcting unit, and a controller. The optical scanner is disposed at an optically substantially conjugate position with a first site of a subject's eye. The interference optical system is configured to split light from a light source into reference light and measurement light, to project the measurement light onto the subject's eye via the optical scanner, and to detect interference light between returning light of the light from the subject's eye and the reference light via the optical scanner. The image forming unit is configured to form a tomographic image of the subject's eye corresponding a first traveling direction of the measurement light deflected by the optical scanner, based on a detection result of the interference light. The intraocular distance calculator is configured to obtain an intraocular distance between predetermined sites of the subject's eye based on the detection result of the interference light. The image correcting unit is configured to correct the tomographic image based on the intraocular distance. The controller is configured to control at least the optical scanner.

A fundus imaging apparatus includes an illumination apparatus including a light source and an illumination optical system, and an imaging apparatus including an image sensor and an imaging optical system. The illumination optical system irradiates a fundus with light from the light source. The imaging optical system forms an image of the fundus on the image sensor. An optical axis of the illumination optical system does not match an optical axis of the imaging optical system, or the illumination optical system does not have a specific optical axis.

A fundus imaging apparatus includes an illumination apparatus including a light source and an illumination optical system, and an imaging apparatus including an image sensor and an imaging optical system. The illumination optical system irradiates a fundus with light from the light source. The imaging optical system forms an image of the fundus on the image sensor. An optical axis of the illumination optical system does not match an optical axis of the imaging optical system, or the illumination optical system does not have a specific optical axis.

In the ophthalmic imaging apparatus of an aspect example, the first image collecting unit collects a series of Scheimpflug images by performing scanning of a three dimensional region of a subject's eye with slit light. The second image collecting unit collects a series of time series images by performing repetitive photography of the subject's eye in parallel with the scanning of the three dimensional region performed by the first image collecting unit. The first image analyzing unit analyzes the series of time series images to determine time series shifts of the slit light during the scanning of the three dimensional region performed by the first image collecting unit. The image interpolating unit performs interpolation of the series of Scheimpflug images based on the time series shifts of the slit light determined by the first image analyzing unit.

In the ophthalmic imaging apparatus of an aspect example, the first image collecting unit collects a series of Scheimpflug images by performing scanning of a three dimensional region of a subject's eye with slit light. The second image collecting unit collects a series of time series images by performing repetitive photography of the subject's eye in parallel with the scanning of the three dimensional region performed by the first image collecting unit. The first image analyzing unit analyzes the series of time series images to determine time series shifts of the slit light during the scanning of the three dimensional region performed by the first image collecting unit. The image interpolating unit performs interpolation of the series of Scheimpflug images based on the time series shifts of the slit light determined by the first image analyzing unit.

The present disclosure provides a system for predicting diabetic retinopathy progression. The system includes an image-capturing module and a processing unit. The image-capturing module is configured to capture a first fundus image of a user at a first time and a second fundus image of the user at a second time different from the first time. The processing unit is configured to receive the first fundus image and the second fundus image, compare the first fundus image and the second fundus image and indicate a difference between the first fundus image and the second fundus image. The processing unit is also configured to provide a prediction in a diabetic retinopathy progression of the user based on the difference. A method for predicting diabetic retinopathy progression is also provided in the present disclosure.