A target surface in an eye is located using a dual aiming beam apparatus that transmits a first aiming beam of light and a second aiming beam of light. An optics subsystem receives a laser beam from a laser source, the first aiming beam of light, and the second aiming beam of light, and directs the beams of light to be incident with the target surface and aligns the beams of light such that they intersect at a point corresponding to a focus of the laser beam. An imaging apparatus captures an image of the target surface including a first spot corresponding to the first aiming beam of light and a second spot corresponding to a second aiming beam of light. A separation between the spots indicates that the focus is away from the target surface, while overlapping spots indicate the focus is at or on the target surface.

Disclosed is an eye examination apparatus that can be used in professional settings. The eye examination apparatus has a body having a first eye opening and a second eye opening for a user to see into the eye examination apparatus using two eyes. The eye examination apparatus also has a first camera coupled to the body and positioned to acquire ophthalmic images through the first eye opening, and a second camera coupled to the body and positioned to acquire ophthalmic images through the second eye opening. The eye examination apparatus also has at least one display coupled to the body and positioned to be viewable through the first eye opening and the second eye opening.

Disclosed is an eye examination apparatus that can be used in professional settings. The eye examination apparatus has a body having a first eye opening and a second eye opening for a user to see into the eye examination apparatus using two eyes. The eye examination apparatus also has a first camera coupled to the body and positioned to acquire ophthalmic images through the first eye opening, and a second camera coupled to the body and positioned to acquire ophthalmic images through the second eye opening. The eye examination apparatus also has at least one display coupled to the body and positioned to be viewable through the first eye opening and the second eye opening.

An eye imaging system can include a head-wearable fundus camera positioning helmet with an outer shell and a conformable liner that can include head location fiducials defining a specified plane. An attached articulating fundus camera fixture can include a fundus camera positioning indication system to indicate a position of the fundus camera with respect to an eye of the patient for acquiring one or more fundus camera images at the indicated position such that fundus camera images recorded over a chronic period of time are assessable using the position information from the fundus camera positioning indication system. The articulating fundus camera fixture can include an articulating arm and a fundus camera mount. The system can assist the patient with helmet positioning, and can automatically position the fundus camera for accurate image capture and analysis, such as using a trained machine learning model for patient evaluation, monitoring, or diagnosis.

An eye imaging system can include a head-wearable fundus camera positioning helmet with an outer shell and a conformable liner that can include head location fiducials defining a specified plane. An attached articulating fundus camera fixture can include a fundus camera positioning indication system to indicate a position of the fundus camera with respect to an eye of the patient for acquiring one or more fundus camera images at the indicated position such that fundus camera images recorded over a chronic period of time are assessable using the position information from the fundus camera positioning indication system. The articulating fundus camera fixture can include an articulating arm and a fundus camera mount. The system can assist the patient with helmet positioning, and can automatically position the fundus camera for accurate image capture and analysis, such as using a trained machine learning model for patient evaluation, monitoring, or diagnosis.

A system for and a method of analyzing a corneal lesion using an anterior segment image according to the present invention. The system includes: an image acquisition unit configured to acquire an anterior segment image from the eyeball of a subject, a feature extractor configured to extract feature information on a position and a cause of a lesion in the cornea from the anterior segment image by applying a convolution layer to the anterior segment image through machine learning on the basis of a database in which clinical information pre-acquired by analyzing positions and causes of lesions in the corneas of subjects is stored; and a result determination unit configured to identify a position of the cornea from the anterior segment image using the feature information and to analyze and determine the position and the cause of the lesion in the cornea from the position of the cornea.

A diagnosis method includes: (a) checking tear film break-up time point and location by photographing cornea of the subject's eye and checking in time series at least one or more times of the tear film break-up time point; (b) checking corneal surface temperature by measuring the surface temperature of the cornea of the subject to be evaluated using a thermal imaging camera performed simultaneously with the photographing of the tear film of the eye; (c) mapping the tear film break-up time point and the change in the surface temperature of the cornea based on time; and (d) diagnosing type of dry eye syndrome based on any one of the tear film break-up time point and a location of surface temperature change time point of the corneal corresponding thereto, in mapping result in step (c).

A diagnosis method includes: (a) checking tear film break-up time point and location by photographing cornea of the subject's eye and checking in time series at least one or more times of the tear film break-up time point; (b) checking corneal surface temperature by measuring the surface temperature of the cornea of the subject to be evaluated using a thermal imaging camera performed simultaneously with the photographing of the tear film of the eye; (c) mapping the tear film break-up time point and the change in the surface temperature of the cornea based on time; and (d) diagnosing type of dry eye syndrome based on any one of the tear film break-up time point and a location of surface temperature change time point of the corneal corresponding thereto, in mapping result in step (c).

An ophthalmic apparatus includes an illumination optical system including a slit in which a slit-shaped aperture is formed and an iris aperture in which two apertures are formed at positions away from an optical axis position, the iris aperture being arranged at a position substantially conjugate optically to an iris of a subject's eye between a light source and the slit, and configured to generate slit-shaped illumination light using light from the light source and to guide the illumination light to a fundus of the subject's eye; and an imaging optical system including an imaging aperture in which an aperture is formed, and configured to guide returning light of the illumination light to an image sensor, the returning light being guided from the fundus by pupil division and passing through the aperture formed in the imaging aperture. A width of the slit-shaped aperture, a distance between the two apertures, and a size of the aperture in the imaging aperture are set so that an overlap region of a light flux region of the illumination light and a light flux region of the returning light is located on a side of the fundus from a posterior surface of lens of the subject's eye within the eye of the subject eye.

An ophthalmic apparatus includes an illumination optical system including a slit in which a slit-shaped aperture is formed and an iris aperture in which two apertures are formed at positions away from an optical axis position, the iris aperture being arranged at a position substantially conjugate optically to an iris of a subject's eye between a light source and the slit, and configured to generate slit-shaped illumination light using light from the light source and to guide the illumination light to a fundus of the subject's eye; and an imaging optical system including an imaging aperture in which an aperture is formed, and configured to guide returning light of the illumination light to an image sensor, the returning light being guided from the fundus by pupil division and passing through the aperture formed in the imaging aperture. A width of the slit-shaped aperture, a distance between the two apertures, and a size of the aperture in the imaging aperture are set so that an overlap region of a light flux region of the illumination light and a light flux region of the returning light is located on a side of the fundus from a posterior surface of lens of the subject's eye within the eye of the subject eye.