This disclosure provides multifunctional conjugate molecules in which at least one -lactam antibiotic is covalently attached to a cannabinoid by means of a linker. The disclosed conjugate molecules are designed to deliver therapeutic benefits as intact molecules, with release of the cannabinoid upon binding of the -lactam antibiotic to its target conveying further therapeutic benefits, and can be used to treat bacterial infections and other disorders.

This disclosure provides multifunctional conjugate molecules in which at least one -lactam antibiotic is covalently attached to a cannabinoid by means of a linker. The disclosed conjugate molecules are designed to deliver therapeutic benefits as intact molecules, with release of the cannabinoid upon binding of the -lactam antibiotic to its target conveying further therapeutic benefits, and can be used to treat bacterial infections and other disorders.

This disclosure provides multifunctional conjugate molecules in which at least one -lactam antibiotic is covalently attached to a cannabinoid by means of a linker. The disclosed conjugate molecules are designed to deliver therapeutic benefits as intact molecules, with release of the cannabinoid upon binding of the -lactam antibiotic to its target conveying further therapeutic benefits, and can be used to treat bacterial infections and other disorders.

This disclosure provides multifunctional conjugate molecules in which at least one -lactam antibiotic is covalently attached to a cannabinoid by means of a linker. The disclosed conjugate molecules are designed to deliver therapeutic benefits as intact molecules, with release of the cannabinoid upon binding of the -lactam antibiotic to its target conveying further therapeutic benefits, and can be used to treat bacterial infections and other disorders.

Beta-lactam compounds to detect carbapenemases or microbial carbapenem resistance are disclosed. The compounds contain a chemical probe. Upon hydrolysis by carbapenemases, the compounds undergo intramolecular rearrangement and release the chemical probe. Detection of the released chemical probe indicates the presence of carbapenemases and the presence of microbial carbapenem resistance.

Beta-lactam compounds to detect carbapenemases or microbial carbapenem resistance are disclosed. The compounds contain a chemical probe. Upon hydrolysis by carbapenemases, the compounds undergo intramolecular rearrangement and release the chemical probe. Detection of the released chemical probe indicates the presence of carbapenemases and the presence of microbial carbapenem resistance.