The present disclosure provides compounds represented by Formula (I) and the pharmaceutically acceptable salts and solvates thereof, wherein R.sup.1a, R.sup.1b, R.sup.3a, R.sup.4, A, E.sup.1, E.sup.2, M, and Q are as set forth in the specification. Compounds of Formula (I) are STAT protein degraders and thus are useful for the treatment of cancer and other diseases. ##STR00001##

The present invention provides compounds, compositions thereof, and methods of using the same.

Alkoxylation reactions are performed in the presence of a phosphonium catalyst having the structure P.sup.+(XR.sup.1R.sup.2R.sup.3)A.sup.1 wherein R.sup.1 is a group having an unsubstituted or inertly substituted aromatic five-member ring having a direct bond between an atom of the aromatic five-member ring and the phosphorus atom, and each R.sup.2 is independently a group having an unsubstituted or inertly substituted, optionally heteroatomic, aromatic five- or six-member ring having a direct bond between a carbon atom of the optionally heteroatomic aromatic five- or six-member ring and the phosphorus atom. X is selected from fluorine, chlorine, bromine, iodine, C.sub.1-12 perfluoroalkyl, C.sub.1-12 alkyl, aryloxy and C.sub.1-12 alkoxy, and A is a weakly coordinating anion.

The present invention relates to hydroxyamino phosphinic acid derivatives of formula I

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in which the occurring groups and parameters have the meanings defined in claim 1, to a method for their preparation and to their use for the fabrication of self-assembled monolayers (SAM), in particular for the fabrication of switchable SAM for electronic devices. The invention further relates to electronic devices comprising said SAM, preferably in the field of organic electronics, in particular for use in memory, sensors, furthermore in organic light-emitting diodes (OLEDs), photovoltaics (OPVs), field-effect transistors (OFETs) and Josephson junctions, very particularly in memristive components such as memristive crossbar-arrays.