C07K14/26

KLEBSIELLA VACCINE AND METHODS OF USE
20220257743 · 2022-08-18 ·

Provided are compositions and methods that include a K. pneumoniae yidR protein or an antigenic segment of the protein, and homologous of the protein, and antigenic segments of the homologs. The compositions can be provided as vaccine formulations for use with humans and non-human animals, including but not limited to dairy cows. The compositions and methods are useful for prophylaxis and/or therapy of conditions associated with Gram negative bacteria that include K. pneumonia, E. coli, and other pathogenic Gram negative bacteria. The conditions include such bacterial infections generally, and include specifically mastitis and metritis. The compositions and methods can also improve fertility and milk production. Administration of the compositions can improve the likelihood of a first service conception.

BINDING MOIETIES FOR BIOFILM REMEDIATION

Binding agents able to disrupt bacterial biofilms of diverse origin are described, including monoclonal antibodies secreted by human B lymphocytes. Methods to prevent formation of or to dissolve biofilms with these binding agents are also described. Immunogens for eliciting antibodies to disrupt biofilms are also described.

IMMUNOGENIC COMPOSITIONS

Technologies for the prevention and/or treatment of nosocomial infections.

IMMUNOGENIC COMPOSITIONS

Technologies for the prevention and/or treatment of nosocomial infections.

PROTEINS AND IMMUNIZING COMPOSITIONS CONTAINING KLEBSIELLA PROTEINS AND METHODS OF USE
20210330776 · 2021-10-28 ·

Provided herein are isolated proteins isolatable from a Klebsiella spp. Also provided are compositions that include one or more of the proteins, and methods for making and methods for using the proteins.

PROTEINS AND IMMUNIZING COMPOSITIONS CONTAINING KLEBSIELLA PROTEINS AND METHODS OF USE
20210330776 · 2021-10-28 ·

Provided herein are isolated proteins isolatable from a Klebsiella spp. Also provided are compositions that include one or more of the proteins, and methods for making and methods for using the proteins.

Methods and compositions for improved production of fatty acids and derivatives thereof

The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, and engineered host cells for producing fatty acids and derivates of fatty acids such as acyl-CoA, terminal olefins, fatty aldehydes, fatty alcohols, alkanes, alkenes, wax esters, ketones and internal olefins through altered expression of the transcription factor, fadR.

RECOMBINANT MICROORGANISM CAPABLE OF SIMULTANEOUS FERMENTATION OF MIXED SUGARS AND METHOD FOR PRODUCING DIOL USING SAME
20210171960 · 2021-06-10 ·

The present invention relates to a recombinant microorganism which is capable of simultaneously fermenting at least two sugars in a lignocellulosic saccharified liquid, and also capable of generating diol.

RECOMBINANT MICROORGANISM CAPABLE OF SIMULTANEOUS FERMENTATION OF MIXED SUGARS AND METHOD FOR PRODUCING DIOL USING SAME
20210171960 · 2021-06-10 ·

The present invention relates to a recombinant microorganism which is capable of simultaneously fermenting at least two sugars in a lignocellulosic saccharified liquid, and also capable of generating diol.

ESCHERICHIA COLI COMPOSITIONS AND METHODS THEREOF
20210268095 · 2021-09-02 · ·

This invention provides a polypeptide derived from E. coli or a fragment thereof, including compositions and methods thereof. In one embodiment, the compositions comprise a polypeptide derived from E. coli or a fragment thereof; and modified O-polysaccharide molecules derived from E. coli lipopolysaccharides or conjugates thereof. In a further aspect, the compositions further comprise modified O-polysaccharide molecules derived from Klebsiella pneumoniae or conjugates thereof.