Patent classifications
C07K14/26
Proteins and immunizing compositions containing <i>Klebsiella </i>proteins and methods of use
Provided herein are isolated proteins isolatable from a Klebsiella spp. Also provided are compositions that include one or more of the proteins, and methods for making and methods for using the proteins.
Proteins and immunizing compositions containing <i>Klebsiella </i>proteins and methods of use
Provided herein are isolated proteins isolatable from a Klebsiella spp. Also provided are compositions that include one or more of the proteins, and methods for making and methods for using the proteins.
SYNTHETIC GENE CLUSTERS
Methods for making synthetic gene clusters are described.
SYNTHETIC GENE CLUSTERS
Methods for making synthetic gene clusters are described.
Method to detect autoantibody reactivity for deamidated insulin autoantigen in diabetes
Provided herein are epitopes and mimotopes thereof useful in the diagnosis and treatment of type 1 diabetes (T1D), as well as antibodies recognizing such epitopes, and diagnostics, therapeutics, kits, and methods of use thereof.
Proteins and nucleic acids useful in vaccines targeting Klebsiella pneumoniae
The present invention relates to proteins and nucleic acids derived from Klebsiella pneumoniae as well as therapeutic and diagnostic uses of the proteins and nucleic acids.
Proteins and nucleic acids useful in vaccines targeting Klebsiella pneumoniae
The present invention relates to proteins and nucleic acids derived from Klebsiella pneumoniae as well as therapeutic and diagnostic uses of the proteins and nucleic acids.
Klebsiella Pneumoniae O-Antigen Glycosylated Proteins and Methods of Making and Uses Thereof
Provided herein is a bioconjugate comprising a K. pneumoniae O-antigen covalently linked to a fusion protein comprising a ComP protein or a glycosylation tag fragment. The K. pneumoniae O-antigen bioconjugate of this disclosure can be used as a conjugate vaccine including multivalent conjugate vaccines comprising multiple K. pneumoniae O-antigens.
Klebsiella Pneumoniae O-Antigen Glycosylated Proteins and Methods of Making and Uses Thereof
Provided herein is a bioconjugate comprising a K. pneumoniae O-antigen covalently linked to a fusion protein comprising a ComP protein or a glycosylation tag fragment. The K. pneumoniae O-antigen bioconjugate of this disclosure can be used as a conjugate vaccine including multivalent conjugate vaccines comprising multiple K. pneumoniae O-antigens.
Proteins and nucleic acids useful in vaccines targeting Klebsiella pneumoniae
The present invention relates to proteins and nucleic acids derived from Klebsiella pneumonia as well as therapeutic and diagnostic uses of the proteins and nucleic acids.