C07K14/77

ERYTHROCYTE-BINDING THERAPEUTICS
20190382479 · 2019-12-19 ·

Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired. Fusions with targeting peptides direct the fusions to the target, for instance a tumor, where the erythrocyte-binding ligands reduce or entirely eliminate blood flow to the tumor by recruiting erythrocytes to the target.

ERYTHROCYTE-BINDING THERAPEUTICS
20190382479 · 2019-12-19 ·

Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired. Fusions with targeting peptides direct the fusions to the target, for instance a tumor, where the erythrocyte-binding ligands reduce or entirely eliminate blood flow to the tumor by recruiting erythrocytes to the target.

METHODS AND COMPOSITIONS FOR EGG WHITE PROTEIN PRODUCTION
20240083977 · 2024-03-14 · ·

Provided herein are compositions, proteins, polynucleotides, expression vectors, host cells, kits, and systems for producing egg white proteins, as well as methods of using the same.

METHODS AND COMPOSITIONS FOR EGG WHITE PROTEIN PRODUCTION
20240083977 · 2024-03-14 · ·

Provided herein are compositions, proteins, polynucleotides, expression vectors, host cells, kits, and systems for producing egg white proteins, as well as methods of using the same.

METHODS AND COMPOSITIONS FOR EGG WHITE PROTEIN PRODUCTION
20240083978 · 2024-03-14 · ·

Provided herein are compositions, proteins, polynucleotides, expression vectors, host cells, kits, and systems for producing egg white proteins, as well as methods of using the same.

METHODS AND COMPOSITIONS FOR EGG WHITE PROTEIN PRODUCTION
20240083978 · 2024-03-14 · ·

Provided herein are compositions, proteins, polynucleotides, expression vectors, host cells, kits, and systems for producing egg white proteins, as well as methods of using the same.

COMPOSITIONS, METHODS AND SYSTEMS FOR PRODUCTION OF EGG WHITE PROTEINS IN PLANTS
20240049754 · 2024-02-15 · ·

Compositions, methods and systems for producing recombinant egg white proteins, as well as transgenic plants and food compositions comprising recombinant egg white proteins, including tagged proteins comprising egg white proteins with additional amino acids. Egg white proteins can be mixed with plant proteins to produce food products.

COMPOSITIONS, METHODS AND SYSTEMS FOR PRODUCTION OF EGG WHITE PROTEINS IN PLANTS
20240049754 · 2024-02-15 · ·

Compositions, methods and systems for producing recombinant egg white proteins, as well as transgenic plants and food compositions comprising recombinant egg white proteins, including tagged proteins comprising egg white proteins with additional amino acids. Egg white proteins can be mixed with plant proteins to produce food products.

PHAGE-DERIVED PARTICLES FOR IN SITU DELIVERY OF DNA PAYLOAD INTO C. ACNES POPULATION

The invention relates to C. acnes carrying DNA vectors with a C. acnes phage packaging signal and a gene of interest. The invention encompasses a C. acnes producer cell carrying DNA vectors, with a C. acnes phage packaging signal and a gene of interest, for the production of phage-derived particles that can robustly transduce C. acnes receiver cell allowing transgene expression. The invention encompasses C. acnes phage-derived particles carrying these vectors, C. acnes containing these vectors or modified by transduction of these phage-derived particles, and methods of using these phage-derived particles.

PHAGE CONJUGATES AND USES THEREOF

The present invention relates to pharmaceutical compositions containing lipid-bacteriophage conjugates, wherein the bacteriophage:lipid ratio is in the range of 3:1 to 100:1 and wherein the lipid is an immunologically active lipid and the bacteriophage is a filamentous bacteriophage, and uses thereof. Preferably, the bacteriophage is engineered to stimulate an immune response and/or bind to a target cell.