A first aspect of the disclosure relates to the field of binding molecules targeted at pathogens. The disclosure further relates to proteinaceous binding molecules targeting cells displaying pathogen-associated molecular patterns, in particular targeting cell surface molecules associated with or derived from pathogens, more in particular cell surface proteins displaying peptides from intracellular (pathogen associated) proteins.

Disclosed is an antibody that specifically binds to a Strep-Tag II tag, and further disclosed are an amino acid sequence of the antibody of the present invention, a cloning or expression vector, a host cell, and a method for expressing or separating the antibody, and also disclosed is a composition comprising the antibody of the present invention. Also disclosed is a method for detecting or purifying a biological sample expressing the Strep-Tag II Tag by means of using the antibody of the present invention.