A peptide-polymer conjugate prepared by a method for preparing a peptide-polymer conjugate according to the present disclosure stably maintains the two-dimensional structure of multiple -helix ligands so that its biological interaction is improved while maintaining the specific structure of the peptide ligands.

A peptide-polymer conjugate prepared by a method for preparing a peptide-polymer conjugate according to the present disclosure stably maintains the two-dimensional structure of multiple -helix ligands so that its biological interaction is improved while maintaining the specific structure of the peptide ligands.

The present disclosure relates to a corneal implant comprising a matrix material and a core part wherein the core part is arranged essentially in the middle of the matrix material. The core part is anti fouling in order to stop cell proliferation across said part. The present disclosure further relates to a method of preparing the said product and the use of the same.

The present disclosure relates to a corneal implant comprising a matrix material and a core part wherein the core part is arranged essentially in the middle of the matrix material. The core part is anti fouling in order to stop cell proliferation across said part. The present disclosure further relates to a method of preparing the said product and the use of the same.

A novel photocurable resin composition including: a polymer with a weight average molecular weight of 1,000 to 50,000, the polymer having a structural unit of formula (1), and having a structure of formula (2) at an end: wherein X is a C.sub.1-6 alkyl group, vinyl group, allyl group, or glycidyl group; m and n are each independently 0 or 1; Q is a divalent hydrocarbon group having a carbon atom number of 1 to 16; Z is a divalent linking group having a carbon atom number of 1 to 4, wherein the divalent linking group is attached to the O group in formula (1); and R.sup.1 is a hydrogen atom or methyl group; a radical photopolymerization initiator; and a solvent.

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In an aspect, a method of synthesizing a graft copolymer comprises the steps of: copolymerizing a first macromonomer and a first reactive diluent; wherein said first macromonomer comprises a first backbone precursor directly or indirectly covalently linked to a first polymer side chain group; wherein said reactive diluent is provided in the presence of the first macromonomer at an amount selected so as to result in formation said graft copolymer having a first backbone incorporating said diluent and said first macromonomer in a first polymer block characterized by a preselected first graft density or a preselected first graft distribution of said first macromonomer. In some embodiments of this aspect, said preselected first graft density is any value selected from the range of 0.05 to 0.75. In some methods, the composition and amount of said diluent is selected to provide both a first preselected first graft density and a first preselected first graft distribution.

The present disclosure relates to a hydrogel derived from a methacrylated or acrylated natural polymer and a synthetic polymer, and a method of preparing the same. The disclosure further relates to 3D scaffolds and implants comprising said hydrogel.

The present disclosure relates to a hydrogel derived from a methacrylated or acrylated natural polymer and a synthetic polymer, and a method of preparing the same. The disclosure further relates to 3D scaffolds and implants comprising said hydrogel.

Non-silicone urea-based adhesives are disclosed which are prepared by the polymerization of reactive oligomers with the general formula XBX, where X is an ethylenically unsaturated group and B is a unit free of silicone and containing urea groups. The reactive oligomers can be prepared from polyamines through chain extension reactions using diaryl carbonates followed by capping reactions. Adhesive articles, including optical adhesive articles may be prepared using the disclosed non-silicone urea-based adhesives.

A peptide-polymer conjugate prepared by a method for preparing a peptide-polymer conjugate according to the present disclosure stably maintains the two-dimensional structure of multiple -helix ligands so that its biological interaction is improved while maintaining the specific structure of the peptide ligands.