Described are silicone hydrogels that are more biocompatible than current ocular materials. The silicone hydrogels are formed from a reactive monomer mixture comprising: a mixture of hydroxyl substituted silicone containing components, at least one polyamide; and at least one hydrophilic monomer. The silicone hydrogels also display a desirable balance of properties, including clarity, oxygen permeability, wettability and desirable protein uptake.

Provided are a composition for forming an imprint pattern, containing a polymerizable compound, a polymerization initiator, and a derivative of the polymerization initiator; a cured substance of the composition for forming an imprint pattern; a device including the cured substance; an imprint pattern producing method using the composition for forming an imprint pattern; and a method for manufacturing a device, including the imprint pattern producing method.

A block copolymer is provided that includes a first block having pendant phosphate and/or phosphonate groups and a second block that contains pendant poly(dialkylsiloxane) groups. Compositions containing the block copolymer as well as articles that include the block copolymer are also provided. The block copolymer can be used to provide a surface that is easy to clean and/or that is resistant to oil and grease without the use of fluorinated materials.

A block copolymer is provided that includes a first block having pendant phosphate and/or phosphonate groups and a second block that contains pendant poly(dialkylsiloxane) groups. Compositions containing the block copolymer as well as articles that include the block copolymer are also provided. The block copolymer can be used to provide a surface that is easy to clean and/or that is resistant to oil and grease without the use of fluorinated materials.

The invention is generally related to a method for producing coated silicone hydrogel contact lenses each of which has a hydrogel coating thereon and a relative high resistance to uptakes of polycationic antimicrobials as characterized by having a polyquaternium-1-uptake of less than 0.40 micrograms/lens. The hydrogel coating is formed by covalently attached a hydrophilic polymeric material onto a base coating of a polyanionic polymer on a SiHy contact lens. In this method, lower polyquaternium-1-uptake is achieved by using a rinse solution with a higher pH and/or a higher ionic strength (higher salt concentration) for rinsing a treated silicone hydrogel contact lens with a base coating of polyanionic polymer.

The invention is generally related to a method for producing coated silicone hydrogel contact lenses each of which has a hydrogel coating thereon and a relative high resistance to uptakes of polycationic antimicrobials as characterized by having a polyquaternium-1-uptake of less than 0.40 micrograms/lens. The hydrogel coating is formed by covalently attached a hydrophilic polymeric material onto a base coating of a polyanionic polymer on a SiHy contact lens. In this method, lower polyquaternium-1-uptake is achieved by using a rinse solution with a higher pH and/or a higher ionic strength (higher salt concentration) for rinsing a treated silicone hydrogel contact lens with a base coating of polyanionic polymer.

One of the purposes of the present invention is to provide a silicone which has polymerizable groups at the both terminals and an amphiphilic side chain and which provides a copolymer having high surface wettability. The present invention provides a silicone represented by the formula (1): in the formula (1) R.sup.1 is a group represented by the following formula (2): wherein n is an integer of 2 to 8 and R.sup.4 is a methyl group or a hydrogen atom, “a” is an integer of 1 to 500, b is an integer of 1 to 100, provided that a+b is 50 to 600, the siloxane units in the aforesaid parentheses may be bonded in a block or at random, R.sup.2 is, independently of each other, a substituted or unsubstituted monovalent hydrocarbon group having 1 to 10 carbon atoms, R.sup.3 is, independently of each other, an alkyl group having 1 to 6 carbon atoms, A.sup.1 is a group represented by the formula (3) or (3′): wherein R is a hydrogen atom or a methyl group, B.sup.1 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, an aralkyl group having 7 to 12 carbon atoms, or an acyl group having 1 to 6 carbon atoms, m is an integer of 0 to 8, p is an integer of 1 to 10, q is an integer of 1 to 50, and the polyether units in the parentheses are bonded in the above-described order.

One of the purposes of the present invention is to provide a silicone which has polymerizable groups at the both terminals and an amphiphilic side chain and which provides a copolymer having high surface wettability. The present invention provides a silicone represented by the formula (1): in the formula (1) R.sup.1 is a group represented by the following formula (2): wherein n is an integer of 2 to 8 and R.sup.4 is a methyl group or a hydrogen atom, “a” is an integer of 1 to 500, b is an integer of 1 to 100, provided that a+b is 50 to 600, the siloxane units in the aforesaid parentheses may be bonded in a block or at random, R.sup.2 is, independently of each other, a substituted or unsubstituted monovalent hydrocarbon group having 1 to 10 carbon atoms, R.sup.3 is, independently of each other, an alkyl group having 1 to 6 carbon atoms, A.sup.1 is a group represented by the formula (3) or (3′): wherein R is a hydrogen atom or a methyl group, B.sup.1 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, an aralkyl group having 7 to 12 carbon atoms, or an acyl group having 1 to 6 carbon atoms, m is an integer of 0 to 8, p is an integer of 1 to 10, q is an integer of 1 to 50, and the polyether units in the parentheses are bonded in the above-described order.

A (meth)acrylic copolymer of the present invention includes at least one constituent unit (A) selected from the group consisting of a constituent unit (A1) having at least one structure (I) represented by Formula (1), Formula (2), or Formula (3), a constituent unit (A2) containing a triorganosilyloxycarbonyl group, and a constituent unit (A3) having at least one structure (III) represented by Formula (4) or Formula (5), a constituent unit (B) derived from a specific polysiloxane block-containing polymerizable monomer (b), and a constituent unit (C) derived from a macromonomer (c).

A (meth)acrylic copolymer of the present invention includes at least one constituent unit (A) selected from the group consisting of a constituent unit (A1) having at least one structure (I) represented by Formula (1), Formula (2), or Formula (3), a constituent unit (A2) containing a triorganosilyloxycarbonyl group, and a constituent unit (A3) having at least one structure (III) represented by Formula (4) or Formula (5), a constituent unit (B) derived from a specific polysiloxane block-containing polymerizable monomer (b), and a constituent unit (C) derived from a macromonomer (c).