The invention relates to the discovery of tissue mimicking constructs and compositions that can be used to study the growth and development of cells in vitro. In certain embodiments, the invention provides methods of culturing cells on the tissue mimicking polymer microspheres. In other embodiments, the invention provides methods of treating a disease or disorder using the compositions and constructs of the invention.

This invention relates to novel macromers comprise the reaction product of a starter compound having a functionality of 2 to 8 and a hydroxyl number of 20 to 50, with a modified isocyanate component. This invention also relates to preformed stabilizers prepared from these macromers, and to polymer polyols prepared from these novel macromers and novel preformed stabilizers. The present invention also relates to processes for preparing these compositions, to polyurethane foams comprising these polymer polyols, and to processes for preparing these polyurethane foams.

This invention relates to novel macromers comprise the reaction product of a starter compound having a functionality of 2 to 8 and a hydroxyl number of 20 to 50, with a modified isocyanate component. This invention also relates to preformed stabilizers prepared from these macromers, and to polymer polyols prepared from these novel macromers and novel preformed stabilizers. The present invention also relates to processes for preparing these compositions, to polyurethane foams comprising these polymer polyols, and to processes for preparing these polyurethane foams.

This invention relates to novel macromers comprise the reaction product of a starter compound having a functionality of 2 to 8 and a hydroxyl number of 20 to 50, with a modified isocyanate component. This invention also relates to preformed stabilizers prepared from these macromers, and to polymer polyols prepared from these novel macromers and novel preformed stabilizers. The present invention also relates to processes for preparing these compositions, to polyurethane foams comprising these polymer polyols, and to processes for preparing these polyurethane foams.

This invention relates to novel macromers comprise the reaction product of a starter compound having a functionality of 2 to 8 and a hydroxyl number of 20 to 50, with a modified isocyanate component. This invention also relates to preformed stabilizers prepared from these macromers, and to polymer polyols prepared from these novel macromers and novel preformed stabilizers. The present invention also relates to processes for preparing these compositions, to polyurethane foams comprising these polymer polyols, and to processes for preparing these polyurethane foams.

The present invention relates to novel (per)fluoropolyether (PFPE) polymers, to a process for their manufacture and to their use as additives in coating compositions.

A resin composition for underlayer film formation capable of forming an underlayer film having good adhesiveness and excellent surface flatness, a layered product, a method for forming a pattern and a process for producing a device are provided. The resin composition for underlayer film formation includes a resin having a group represented by General Formula (A) and a group represented by General Formula (B), and a solvent. Ra1 represents a hydrogen atom or a methyl group, Rb1 and Rb2 each independently represents an unsubstituted linear or branched alkyl group having 1 to 20 carbon atoms or an unsubstituted cycloalkyl group having 3 to 20 carbon atoms, Rb3 represents an unsubstituted linear or branched alkyl group having 2 to 20 carbon atoms or an unsubstituted cycloalkyl group having 3 to 20 carbon atoms, and Rb2 and Rb3 may be bonded to each other to form a ring. ##STR00001##

A resin composition for underlayer film formation capable of forming an underlayer film having good adhesiveness and excellent surface flatness, a layered product, a method for forming a pattern and a process for producing a device are provided. The resin composition for underlayer film formation includes a resin having a group represented by General Formula (A) and a group represented by General Formula (B), and a solvent. Ra1 represents a hydrogen atom or a methyl group, Rb1 and Rb2 each independently represents an unsubstituted linear or branched alkyl group having 1 to 20 carbon atoms or an unsubstituted cycloalkyl group having 3 to 20 carbon atoms, Rb3 represents an unsubstituted linear or branched alkyl group having 2 to 20 carbon atoms or an unsubstituted cycloalkyl group having 3 to 20 carbon atoms, and Rb2 and Rb3 may be bonded to each other to form a ring. ##STR00001##

The presently claimed invention relates to novel monomers which can be used for preparing polymers which are useful as dispersants for pigments and fillers, as wetting agent and as thickening agents in liquid compositions.

The invention provides a class of amphiphilic branched polydiorganosiloxane macromers and the uses thereof. Such a macromer comprises a polydiorganosiloxane polymer chain and two terminal groups free of any ethylenically unsaturated group, wherein the polydiorganosiloxane polymer chain comprises (1) at least 5 dimethylsiloxane units in a consecutive sequence, (2) at least two first siloxane units each having methyl as one of the two substituents of each first siloxane unit and one first organic radical having one sole (meth)acryloyl group as the other substituent, (3) at least one second siloxane unit having methyl as one of the two substituents of the second siloxane unit and one second organic radical, which is free of any ethylenically unsaturated group and comprises one or more hydrophilic groups or polymer chains, as the other substituent.