The disclosure concerns healable polycarbonate resins comprising at least about 5 mol % of disulfide units, articles comprising the healable polycarbonate resin, and methods of activating the healable polycarbonate resin by exposing the healable polycarbonate resin to heat or radiation.

A method of preparing a partially crystalline polycarbonate powder, including: dissolving an amorphous polycarbonate in a halogenated alkane solvent to form a solution; combining the solution with a crystallizing non-solvent that is miscible with the halogenated alkane solvent, under high shear mixing conditions effective to form a partially crystalline polycarbonate precipitate having a D90 particle size of less than 150 micrometers; an average particle diameter of less than or equal to 100 micrometers, or an average particle diameter of 0 to 100 micrometers; and at least 20% crystallinity, or at least 25% crystallinity, or 25 to 35% crystallinity.

Provided are a novel polyorganosiloxane capable of preparing copolycarbonate with improved weather resistance and flowability while maintaining the intrinsic physical properties of polycarbonate resin, and a copolycarbonate prepared by using the same.

Disclosed in the present disclosure is a biodegradable amphiphilic polymer containing disulfide in the side chain, a self-crosslinked polymeric vesicle thereof and an application in the targeted therapy of lung cancer. The polymer is obtained by an activity-controllable ring-opening polymerization based on a cyclic carbonate monomer containing a functional group of dithiolane ring, which has a controllable molecular weight and a narrow molecular weight distribution, and does not require processes of protection and deprotection; the polymer obtained by the ring-opening polymerization of the cyclic carbonate monomer of the present disclosure has biodegradability and can be used to control the drug release system, the prepared lung cancer-targeted reduction-sensitive reversibly-crosslinked polymeric vesicle as a nanomedicine carrier supports stable long circulation in vivo. However, it is highly enriched in lung cancer tissues, enter cells efficiently, and rapidly decrosslinks in the cells to release drugs, so as to kill cancer cells with high potency and specificity and inhibit the growth of tumor effectively without causing toxic and side effects.

A phosphinate copolycarbonate having units of the formula (1) wherein each R.sup.a is independently a halogen atom, C.sub.1-10 alkyl, C.sub.1-10 haloalkyl, C.sub.1-12 alkoxy, C.sub.6-10 aryl, or C.sub.6-12 haloaryl, each X.sup.a is as defined herein, R.sup.e and R.sup.f are independently a halogen atom, C.sub.1-10 alkyl, C.sub.1-10 haloalkyl, C.sub.1-10 alkoxy, C.sub.1-10 haloalkoxy, C.sub.2-10 alkenyl, or C.sub.3-10 cycloalkyl, each R.sup.g is a substituted or unsubstituted C.sub.6-18 aryl, C.sub.1-10 alkyl, C.sub.1-10 haloalkyl, C.sub.1-10 alkoxy, C.sub.1-10 haloalkoxy, C.sub.2-10 alkenyl, C.sub.3-10 cycloalkyl, C.sub.6-10 aryl, or C.sub.6-12 haloaryl, Ar.sup.a and Ar.sup.b are each independently the same or different C.sub.6-18 aryl, a, e, and f are each independently 0 to 4, or 0 to 2 or 0, c is 0 or 1, and x and y represent the molar ratio of each unit in the phosphinate copolycarbonate, and are 0.5:99.5 to 99.5:0.5, or 1:99 to 99:1, or 10:90 to 90:10, or 20:80 to 80:20.

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Provided is a polycarbonate-polyorganosiloxane copolymer including polycarbonate blocks (A-1) each formed of a specific repeating unit and polyorganosiloxane blocks (A-2) each containing a specific repeating unit, wherein the polycarbonate-polyorganosiloxane copolymer satisfies the following expression (F1a):

15wM1(F1a)

wherein wM1 represents the average content of the polyorganosiloxane blocks (A-2) in polycarbonate-polyorganosiloxane copolymers each having a molecular weight determined by using a polycarbonate as a conversion reference of from 56,000 or more to 200,000 or less among polycarbonate-polyorganosiloxane copolymers obtained through the separation of the polycarbonate-polyorganosiloxane copolymer by gel permeation chromatography.

Techniques regarding the synthesis of one or more polymers through one or more ring-opening polymerizations conducted within a flow reactor and facilitated by one or more anionic catalysts are provided. For example, one or more embodiments can comprise a method, which can comprise functionalizing, via a post-polymerization reaction within a flow reactor, a chemical compound by covalently bonding a trimethylsilyl protected thiol to a pendent functional group of the chemical compound in a presence of a catalyst. The pendent functional group can comprise a perfluoroaryl group and a methylene group.

Provided is a polycarbonate-polyorganosiloxane copolymer including polycarbonate blocks (A-1) each formed of a specific repeating unit and polyorganosiloxane blocks (A-2) each containing a specific repeating unit, wherein the polycarbonate-polyorganosiloxane copolymer satisfies the following expression (F1a):

15wM1(F1a)

wherein wM1 represents the average content of the polyorganosiloxane blocks (A-2) in polycarbonate-polyorganosiloxane copolymers each having a molecular weight determined by using a polycarbonate as a conversion reference of from 56,000 or more to 200,000 or less among polycarbonate-polyorganosiloxane copolymers obtained through the separation of the polycarbonate-polyorganosiloxane copolymer by gel permeation chromatography.

Provided is a polycarbonate resin composition, including, with respect to 100 parts by mass of an aromatic polycarbonate resin (A), 0.005 part by mass to 1 part by mass of a phosphorus-based compound (B) having an aryl group, and 0.005 part by mass to 5 parts by mass of a polyether compound (C) having a specific polyoxyalkylene structure, in which: an amount of a compound having a phenol structure produced by decomposition of the phosphorus-based compound (B) 1,500 hours after standing thereof under conditions of 40 C. and a humidity of 90% is 5 mass % or less with respect to the phosphorus-based compound (B); and when a weight of the phosphorus-based compound (B) is measured with a thermogravimetric-differential thermal analysis machine under a nitrogen atmosphere, a temperature at which the weight becomes smaller than the weight before the measurement by 2% is 340 C. or more.

A flame retardant resin composition in which an acrylonitrile-styrene based polymer, into which sulfonic acid groups and/or sulfonate groups have been introduced by sulfonating processing with a sulfonating agent containing less than 3 wt % of moisture, is contained in a resin to be made flame retardant, so that flame retardant properties will be conferred on the resin flame resistant.