The invention generally relates to compositions comprising degradable polymers and methods of making degradable polymers. Specifically, the disclosed degradable polymers comprise a biodegradable polymer backbone, a nitric oxide linker moiety, and a nitric oxide molecule. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

There is provided a hyper-branched polymer represented by the following formula (1) and having a weight-average molecular weight in a range of 1,000 to 1,000,000. In the formula (1), A.sup.1 is a group containing an aromatic ring, A.sup.2 is a group containing an amide group, A.sup.3 is a group containing sulfur, R.sup.0 is hydrogen or a substituted or unsubstituted hydrocarbon group having 1 to 10 carbon atoms, ml is in a range of 0.5 to 11, and n1 is in a range of 5 to 100. ##STR00001##

A fabrication method and application of topological elastomers with highly branched structures, low modulus and high elasticity. The topological elastomers comprise dendritic macromolecules. The fabrication method includes direct crosslinking, post-crosslinking, grafting, and copolymerization. The performance of the elastomer can be easily tuned via changing the topology of the polymer network. The breakthrough of this invention lies in that these topological elastomers with highly branched structures are having low modulus and high elasticity, which would expand its application in the field of elastomer. Notably, the variety of topological elastomers, the versatility of curing chemistries, the availability of a wide variety of monomers, and the various polymerization methods are enabling the fabrication of topological elastomers with feasibility and efficiency.

Certain embodiments comprise administering a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. In certain embodiments, the structure has a modular design, combining a material configured for controlled release of therapeutic, diagnostic, and/or enhancement agents with a structural material necessary for gastric residence but configured for controlled and/or tunable degradation/dissolution to determine the time at which retention shape integrity is lost and the structure passes out of the gastric cavity. For example, in certain embodiments, the residence structure comprises a first elastic component, a second component configured to release an active substance, and, optionally, a linker. In some such embodiments, the linker may be configured to degrade.

The present invention relates to an antibacterial co-polymer comprising a water soluble backbone polymer having in at least one end a dendritic or hyperbranched polymer of generation 1 to 6 wherein at least one functional group comprising a carboxylic amine has been covalently attached to the periphery of the dendritic or hyperbranched polymer. The present invention also relates to said anti-bacterial co-polymer when said co-polymer has been cross-linked with a cross-linking agent and to uses of the cross-linked co-polymer in a hydrogel for the treatment or prevention of bacterial infections, particularly in surgical site infections (SSIs).

The present invention provides a bionic fiber adsorptive material with multi-adsorption sites and a preparation method and use thereof, and the material is rich in multi-adsorption sites (N, O and S). The material is obtained by blending three polyethyleneimine polymers modified by multifunctional groups respectively with a carboxylated nanocellulose and graphene oxide, then adopting a coaxial spinning method based on a principle of imitating spider spinning, and then adopting a post-crosslinking technology. The material has a multilayer structure with the nanocellulose as a skeleton, the graphene oxide as an outer layer, and the three polyethyleneimine polymers modified by the multifunctional groups respectively as an inner layer, and a connection among the layers is a chemical bond connection. Densities of N, O and S adsorption sites of the material according to the present invention are all higher than 5 mmol/g.

Disclosed herein are the water clarification compositions and method of using the disclosed water clarification compositions for clarifying a water system or waste water source. Specifically, the disclosed compositions comprise and methods use multiple charged cationic or anionic compounds that are derived from polyamines through an aza-Michael addition with an activated olefin having an ionic group. The disclosed water clarification methods or compositions are found to be more effective than those methods or compositions including commonly used single quaternary compounds for reducing turbidity in water systems or waste water sources.

The invention relates to novel antimicrobial surfactants and their application in antimicrobial coating systems, in particular water borne coatings. Provided is a method for providing an antimicrobial surfactant, comprising the steps of: (a) providing a hyperbranched polyurea having blocked isocyanates at the end of the polymer branches by the polycondensation of AB.sub.2 monomers; (b) introducing tertiary amine groups by reacting said blocked isocyanates of the hyperbranched polyurea with a tertiary amine compound that is functionalized with —OH, —NH.sub.2, —SH, or —COO—; and (c) quaternization of said tertiary amine groups by reacting with an alkylating agent to obtain a quaternized hyperbranched polymer having antimicrobial surfactant properties.

The present disclosure provides a rotaxane polymer binder containing a polymer based on a rotaxane structure. The polymer binder may further contain a polymer cross-linked with a polar polymer. The polar polymer may be a polymer containing the element F, O or N in a functional group and having high polarity. In addition, the present disclosure provides an electrode containing the rotaxane polymer binder as a binder for a lithium secondary battery, and a secondary battery containing the electrode.

Disclosed herein are the water clarification compositions and method of using the disclosed water clarification compositions for clarifying a water system or waste water source. Specifically, the disclosed compositions comprise and methods use multiple charged cationic or anionic compounds that are derived from polyamines through an aza-Michael addition with an activated olefin having an ionic group. The disclosed water clarification methods or compositions are found to be more effective than those methods or compositions including commonly used single quaternary compounds for reducing turbidity in water systems or waste water sources.